SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ypd'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_A_115A2_2 (HMG-COA REDUCTASE)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	ASN A2175 LEU A2170 ALA A2192 LEU A2168	None	0.78A	1hwiB-2ypdA: undetectable	1hwiB-2ypdA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_C_115C4_2 (HMG-COA REDUCTASE)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	ASN A2175 LEU A2170 ALA A2192 LEU A2168	None	0.78A	1hwiD-2ypdA: undetectable	1hwiD-2ypdA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_D_115D3_1 (HMG-COA REDUCTASE)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	ASN A2175 LEU A2170 ALA A2192 LEU A2168	None	0.78A	1hwiC-2ypdA: undetectable	1hwiC-2ypdA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KF6_N_ACTN803_0 (FUMARATE REDUCTASE FLAVOPROTEIN FUMARATE REDUCTASE IRON-SULFUR PROTEIN)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 6	TRP A2169 ARG A2379 GLY A2196 ASP A2456	None	1.26A	1kf6M-2ypdA: undetectable 1kf6N-2ypdA: undetectable	1kf6M-2ypdA: 20.30 1kf6N-2ypdA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T88_A_CAMA1422_0 (CYTOCHROME P450-CAM)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 7	PHE A2367 VAL A2349 GLY A2350 VAL A2323	None	1.01A	1t88A-2ypdA: undetectable	1t88A-2ypdA: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_J_ACTJ1116_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	LYS A2408 GLU A2412 ILE A2409 GLU A2442	None	0.78A	2j9dJ-2ypdA: undetectable 2j9dK-2ypdA: undetectable 2j9dL-2ypdA: undetectable	2j9dJ-2ypdA: 18.11 2j9dK-2ypdA: 18.11 2j9dL-2ypdA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_J_ACTJ1116_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	LYS A2408 GLU A2412 ILE A2409 GLU A2442	None	0.80A	2j9dJ-2ypdA: undetectable 2j9dK-2ypdA: undetectable 2j9dL-2ypdA: undetectable	2j9dJ-2ypdA: 18.11 2j9dK-2ypdA: 18.11 2j9dL-2ypdA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNI_A_MTKA501_2 (CYTOCHROME P450 2C8)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 8	ILE A2424 ILE A2402 ILE A2409 ARG A2446 VAL A2445	None None None EMT  A3498 ( 3.2A) None	1.48A	2nniA-2ypdA: undetectable	2nniA-2ypdA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N23_A_OBNA1_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 11	GLN A2476 ASN A2470 VAL A2323 PHE A2367 ARG A2379	EMT  A3503 (-4.8A) None None None None	1.33A	3n23A-2ypdA: undetectable	3n23A-2ypdA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N23_C_OBNC1_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 11	GLN A2476 ASN A2470 VAL A2323 PHE A2367 ARG A2379	EMT  A3503 (-4.8A) None None None None	1.33A	3n23C-2ypdA: undetectable	3n23C-2ypdA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_B_NIMB1701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	3 / 3	VAL A2477 VAL A2197 SER A2284	None	0.65A	3n8xB-2ypdA: undetectable	3n8xB-2ypdA: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A99_D_MIYD393_1 (TETX2 PROTEIN)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 5	ILE A2458 GLN A2452 ILE A2451 GLU A2370	None	1.09A	4a99D-2ypdA: undetectable	4a99D-2ypdA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_B_DXCB1473_0 (TRANSLATION ELONGATION FACTOR SELB)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	ILE A2363 GLY A2362 VAL A2322 ARG A2436	None	0.71A	4acbB-2ypdA: undetectable 4acbC-2ypdA: undetectable	4acbB-2ypdA: 22.94 4acbC-2ypdA: 22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 7	VAL A2193 LEU A2460 ASP A2373 LEU A2376	None	0.75A	4l9iA-2ypdA: undetectable	4l9iA-2ypdA: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 6	PHE A2367 ILE A2451 ARG A2379 VAL A2349	None	1.28A	4mk4B-2ypdA: undetectable	4mk4B-2ypdA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 8	LEU A2281 VAL A2197 VAL A2347 LEU A2285	None	0.89A	4pwdA-2ypdA: undetectable	4pwdA-2ypdA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_C_377C401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 6	ASN A2470 GLU A2243 TYR A2348 PHE A2242	None	1.18A	4twdB-2ypdA: undetectable 4twdC-2ypdA: undetectable	4twdB-2ypdA: 21.48 4twdC-2ypdA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_E_377E401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 6	ASN A2470 GLU A2243 TYR A2348 PHE A2242	None	1.14A	4twdD-2ypdA: undetectable 4twdE-2ypdA: undetectable	4twdD-2ypdA: 21.48 4twdE-2ypdA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_H_377H401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 6	ASN A2470 GLU A2243 TYR A2348 PHE A2242	None	1.18A	4twdG-2ypdA: undetectable 4twdH-2ypdA: undetectable	4twdG-2ypdA: 21.48 4twdH-2ypdA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSP_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	4 / 7	VAL A2343 ILE A2345 VAL A2194 ALA A2457	None	0.66A	5ospA-2ypdA: undetectable	5ospA-2ypdA: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_C_DAHC123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	2ypd	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 10	PHE A2367 LEU A2380 GLY A2362 ILE A2363 PHE A2453	None	1.25A	6ebpC-2ypdA: undetectable	6ebpC-2ypdA: 12.40