SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ypf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 VAL A 329
SER A 299
VAL A 295
SER A 333
 None
 1.32A 2j9cA-2ypfA:
undetectable
2j9cB-2ypfA:
undetectable
2j9cC-2ypfA:
undetectable		 2j9cA-2ypfA:
10.07
2j9cB-2ypfA:
10.07
2j9cC-2ypfA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 545
GLN A 515
THR A 513
HIS A 525
 None
 1.11A 2zj0B-2ypfA:
undetectable		 2zj0B-2ypfA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 647
GLN A 617
THR A 615
HIS A 627
 None
 1.27A 2zj0B-2ypfA:
undetectable		 2zj0B-2ypfA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 579
GLN A 549
THR A 547
HIS A 559
 None
 1.25A 3ce6B-2ypfA:
undetectable		 3ce6B-2ypfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 647
GLN A 617
THR A 615
HIS A 627
 None
 1.26A 3ce6B-2ypfA:
undetectable		 3ce6B-2ypfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 545
GLN A 515
THR A 513
HIS A 525
 None
 1.13A 3ce6D-2ypfA:
undetectable		 3ce6D-2ypfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 647
GLN A 617
THR A 615
HIS A 627
 None
 1.25A 3ce6D-2ypfA:
undetectable		 3ce6D-2ypfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 7 GLY A 541
HIS A 538
ILE A 501
VAL A 514
 None
 0.80A 3fi0E-2ypfA:
undetectable		 3fi0E-2ypfA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 5 LEU A 647
GLN A 617
THR A 615
HIS A 627
 None
 1.29A 3n58C-2ypfA:
undetectable		 3n58C-2ypfA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 11 VAL A 310
GLY A 284
ALA A 285
LEU A 307
PRO A 325
 None
 1.01A 3sm2B-2ypfA:
undetectable		 3sm2B-2ypfA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 9 LEU A 799
THR A 800
VAL A 804
GLU A 836
ILE A 807
 None
 1.03A 3tbgD-2ypfA:
undetectable		 3tbgD-2ypfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 8 VAL A 295
VAL A 294
ASP A 256
GLN A 259
 None
 1.16A 3uy4A-2ypfA:
undetectable		 3uy4A-2ypfA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 8 LEU A 260
LYS A 262
VAL A 295
LEU A 241
 None
 1.06A 3v81A-2ypfA:
undetectable		 3v81A-2ypfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 7 ASN A 436
ILE A 471
ASN A 504
ASP A 539
 None
 1.06A 4d39B-2ypfA:
undetectable		 4d39B-2ypfA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 6 ALA A 340
ALA A 306
LEU A 341
THR A 309
 None
 0.94A 4dtzA-2ypfA:
undetectable		 4dtzA-2ypfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 6 ALA A 408
ALA A 374
LEU A 409
THR A 377
 None
 0.95A 4dtzA-2ypfA:
undetectable		 4dtzA-2ypfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2ypf AVRBS3
(Xanthomonas
campestris) 		4 / 6 ALA A 442
ALA A 408
LEU A 443
THR A 411
 None
 0.86A 4dtzA-2ypfA:
undetectable		 4dtzA-2ypfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 12 VAL A 275
ALA A 274
SER A 299
GLY A 303
THR A 283
 None
 1.32A 4mm4A-2ypfA:
undetectable		 4mm4A-2ypfA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 12 LEU A 317
HIS A 321
VAL A 328
ILE A 331
LEU A 347
 None
 1.31A 4yvpB-2ypfA:
undetectable		 4yvpB-2ypfA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 12 LEU A 657
HIS A 661
VAL A 668
ILE A 671
LEU A 687
 None
 1.21A 4yvpB-2ypfA:
undetectable		 4yvpB-2ypfA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2ypf AVRBS3
(Xanthomonas
campestris) 		3 / 3 GLY A 730
LEU A 731
HIS A 729
 None
 0.70A 5u63B-2ypfA:
undetectable		 5u63B-2ypfA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 2ypf AVRBS3
(Xanthomonas
campestris) 		5 / 12 LEU A 238
ILE A 263
GLY A 267
ALA A 237
VAL A 295
 None
 1.05A 6iftA-2ypfA:
undetectable		 6iftA-2ypfA:
16.76