SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		5 / 9 GLY A1043
ILE A1024
CYH A1027
PHE A1077
GLY A1078
 None
 1.04A 3ko0A-2yq0A:
undetectable
3ko0C-2yq0A:
undetectable		 3ko0A-2yq0A:
16.88
3ko0C-2yq0A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		5 / 9 PHE A1077
GLY A1078
GLY A1043
ILE A1024
CYH A1027
 None
 1.08A 3ko0H-2yq0A:
undetectable
3ko0I-2yq0A:
undetectable		 3ko0H-2yq0A:
16.88
3ko0I-2yq0A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		5 / 10 PHE A1077
GLY A1078
GLY A1043
ILE A1024
CYH A1027
 None
 1.03A 3ko0L-2yq0A:
undetectable
3ko0N-2yq0A:
undetectable		 3ko0L-2yq0A:
16.88
3ko0N-2yq0A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		5 / 10 GLY A1043
ILE A1024
CYH A1027
PHE A1077
GLY A1078
 None
 1.04A 3ko0R-2yq0A:
undetectable
3ko0T-2yq0A:
undetectable		 3ko0R-2yq0A:
16.88
3ko0T-2yq0A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		4 / 6 ASP A1049
GLY A1046
ASP A1045
THR A1111
 None
 0.85A 3vqrA-2yq0A:
undetectable		 3vqrA-2yq0A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2yq0 ORF 73
(Human
gammaherpesvirus
8) 		4 / 5 ASP A1049
GLY A1046
ASP A1045
THR A1111
 None
 0.86A 3vqrB-2yq0A:
undetectable		 3vqrB-2yq0A:
14.13