SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_B_CHDB1250_1 (ALCOHOL DEHYDROGENASE)	2yq1	ORF73 (Murid gammaherpesvirus 4)	5 / 11	SER A 219 LEU A 230 LEU A 139 LEU A 185 VAL A 194	None	1.36A	1ee2B-2yq1A: undetectable	1ee2B-2yq1A: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_A_CHDA502_0 (FERROCHELATASE, MITOCHONDRIAL)	2yq1	ORF73 (Murid gammaherpesvirus 4)	4 / 8	MET A 146 LEU A 150 LEU A 217 VAL A 245	None	0.88A	2po5A-2yq1A: undetectable	2po5A-2yq1A: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	2yq1	ORF73 (Murid gammaherpesvirus 4)	4 / 8	MET A 146 LEU A 150 LEU A 217 VAL A 245	None	0.81A	2po5B-2yq1A: undetectable	2po5B-2yq1A: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_M_TRPM1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2yq1	ORF73 (Murid gammaherpesvirus 4)	5 / 9	GLN A 226 VAL A 221 ILE A 189 VAL A 234 VAL A 233	None	1.10A	3fi0M-2yq1A: undetectable	3fi0M-2yq1A: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB1_A_IMNA701_1 (LACTOTRANSFERRIN)	2yq1	ORF73 (Murid gammaherpesvirus 4)	4 / 4	PRO A 179 THR A 181 GLY A 247 THR A 248	None	1.04A	3ib1A-2yq1A: undetectable	3ib1A-2yq1A: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	2yq1	ORF73 (Murid gammaherpesvirus 4)	5 / 12	PRO A 140 LEU A 139 MET A 146 ARG A 147 CYH A 188	None	1.46A	5emlA-2yq1A: undetectable	5emlA-2yq1A: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2yq1	ORF73 (Murid gammaherpesvirus 4)	4 / 6	VAL A 234 LEU A 195 SER A 196 PHE A 168	None	0.98A	5jw1A-2yq1A: undetectable	5jw1A-2yq1A: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_B_RFPB502_2 (RIFAMPIN MONOOXYGENASE)	2yq1	ORF73 (Murid gammaherpesvirus 4)	4 / 6	GLN A 190 VAL A 221 LEU A 139 ARG A 148	None	1.17A	6brdB-2yq1A: undetectable	6brdB-2yq1A: 22.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EE2_B_CHDB1250_1","ALCOHOL DEHYDROGENASE","2yq1","ORF73","Murid gammaherpesvirus 4",5,"SER A 219;LEU A 230;LEU A 139;LEU A 185;VAL A 194","None","1.36A","1ee2B-2yq1A:undetectable","1ee2B-2yq1A:17.05"],["2PO5_A_CHDA502_0","FERROCHELATASE, MITOCHONDRIAL","2yq1","ORF73","Murid gammaherpesvirus 4",4,"MET A 146;LEU A 150;LEU A 217;VAL A 245","None","0.88A","2po5A-2yq1A:undetectable","2po5A-2yq1A:17.77"],["2PO5_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","2yq1","ORF73","Murid gammaherpesvirus 4",4,"MET A 146;LEU A 150;LEU A 217;VAL A 245","None","0.81A","2po5B-2yq1A:undetectable","2po5B-2yq1A:17.77"],["3FI0_M_TRPM1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2yq1","ORF73","Murid gammaherpesvirus 4",5,"GLN A 226;VAL A 221;ILE A 189;VAL A 234;VAL A 233","None","1.10A","3fi0M-2yq1A:undetectable","3fi0M-2yq1A:17.88"],["3IB1_A_IMNA701_1","LACTOTRANSFERRIN","2yq1","ORF73","Murid gammaherpesvirus 4",4,"PRO A 179;THR A 181;GLY A 247;THR A 248","None","1.04A","3ib1A-2yq1A:undetectable","3ib1A-2yq1A:17.54"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","2yq1","ORF73","Murid gammaherpesvirus 4",5,"PRO A 140;LEU A 139;MET A 146;ARG A 147;CYH A 188","None","1.46A","5emlA-2yq1A:undetectable","5emlA-2yq1A:14.11"],["5JW1_A_CELA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","2yq1","ORF73","Murid gammaherpesvirus 4",4,"VAL A 234;LEU A 195;SER A 196;PHE A 168","None","0.98A","5jw1A-2yq1A:undetectable","5jw1A-2yq1A:14.09"],["6BRD_B_RFPB502_2","RIFAMPIN MONOOXYGENASE","2yq1","ORF73","Murid gammaherpesvirus 4",4,"GLN A 190;VAL A 221;LEU A 139;ARG A 148","None","1.17A","6brdB-2yq1A:undetectable","6brdB-2yq1A:22.03"]]