SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yrl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 2yrl KIAA1837 PROTEIN
(Homo
sapiens) 		5 / 10 LEU A  17
VAL A  93
TYR A  71
LYS A  44
LEU A  53
 None
 0.61A 1cqpA-2yrlA:
undetectable
1cqpB-2yrlA:
undetectable		 1cqpA-2yrlA:
24.68
1cqpB-2yrlA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 2yrl KIAA1837 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A  17
VAL A  93
TYR A  71
LEU A  53
 None
 0.63A 1cqpA-2yrlA:
undetectable
1cqpB-2yrlA:
undetectable		 1cqpA-2yrlA:
24.68
1cqpB-2yrlA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 2yrl KIAA1837 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A  17
VAL A  93
TYR A  71
LYS A  44
 None
 0.63A 1cqpA-2yrlA:
undetectable
1cqpB-2yrlA:
undetectable		 1cqpA-2yrlA:
24.68
1cqpB-2yrlA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 2yrl KIAA1837 PROTEIN
(Homo
sapiens) 		4 / 7 ALA A   9
SER A  32
ILE A  37
ASP A  79
 None
 0.98A 1yc5A-2yrlA:
undetectable		 1yc5A-2yrlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2yrl KIAA1837 PROTEIN
(Homo
sapiens) 		5 / 10 VAL A  91
LEU A  53
VAL A  51
VAL A  63
LEU A  26
 None
 1.04A 3gwxA-2yrlA:
undetectable		 3gwxA-2yrlA:
16.03