SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_A_CHDA801_0 (FERROCHELATASE)	2yru	STEROID RECEPTOR RNA ACTIVATOR 1 (Mus musculus)	5 / 12	LEU A 45 LEU A 48 LEU A 87 VAL A 61 VAL A 69	None	1.34A	2qd4A-2yruA: undetectable	2qd4A-2yruA: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR)	2yru	STEROID RECEPTOR RNA ACTIVATOR 1 (Mus musculus)	5 / 12	LEU A 22 LEU A 19 VAL A 18 VAL A 102 LEU A 87	None	1.24A	3m7rA-2yruA: undetectable	3m7rA-2yruA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	2yru	STEROID RECEPTOR RNA ACTIVATOR 1 (Mus musculus)	4 / 7	MET A 99 ILE A 106 VAL A 18 TRP A 52	None	1.45A	4f4dA-2yruA: undetectable	4f4dA-2yruA: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G9B_A_IXXA609_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN ENVELOPE GLYCOPROTEIN)	2yru	STEROID RECEPTOR RNA ACTIVATOR 1 (Mus musculus)	5 / 7	LEU A 57 VAL A 102 LEU A 48 LEU A 19 LEU A 68	None	1.05A	6g9bA-2yruA: undetectable 6g9bB-2yruA: undetectable	6g9bA-2yruA: 23.42 6g9bB-2yruA: 22.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QD4_A_CHDA801_0","FERROCHELATASE","2yru","STEROID RECEPTOR RNA ACTIVATOR 1","Mus musculus",5,"LEU A  45;LEU A  48;LEU A  87;VAL A  61;VAL A  69","None","1.34A","2qd4A-2yruA:undetectable","2qd4A-2yruA:14.53"],["3M7R_A_VDXA425_1","VITAMIN D3 RECEPTOR","2yru","STEROID RECEPTOR RNA ACTIVATOR 1","Mus musculus",5,"LEU A  22;LEU A  19;VAL A  18;VAL A 102;LEU A  87","None","1.24A","3m7rA-2yruA:undetectable","3m7rA-2yruA:21.05"],["4F4D_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","2yru","STEROID RECEPTOR RNA ACTIVATOR 1","Mus musculus",4,"MET A  99;ILE A 106;VAL A  18;TRP A  52","None","1.45A","4f4dA-2yruA:undetectable","4f4dA-2yruA:14.53"],["6G9B_A_IXXA609_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN;ENVELOPE GLYCOPROTEIN","2yru","STEROID RECEPTOR RNA ACTIVATOR 1","Mus musculus",5,"LEU A  57;VAL A 102;LEU A  48;LEU A  19;LEU A  68","None","1.05A","6g9bA-2yruA:undetectable;6g9bB-2yruA:undetectable","6g9bA-2yruA:23.42;6g9bB-2yruA:22.64"]]