SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ys1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2ys1 DYNAMIN-2
(Homo
sapiens) 		4 / 5 LEU A  38
ALA A 111
ILE A   9
SER A 107
 None
 1.10A 2othA-2ys1A:
undetectable		 2othA-2ys1A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2ys1 DYNAMIN-2
(Homo
sapiens) 		4 / 8 ILE A  60
LEU A  14
ILE A  76
PHE A 108
 None
 0.79A 2w9sE-2ys1A:
undetectable		 2w9sE-2ys1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 2ys1 DYNAMIN-2
(Homo
sapiens) 		4 / 6 LEU A  93
GLU A  92
ASN A  18
ILE A  16
 None
 0.88A 4ww7A-2ys1A:
undetectable		 4ww7A-2ys1A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 2ys1 DYNAMIN-2
(Homo
sapiens) 		4 / 7 ILE A  19
TYR A  29
GLY A  24
LYS A  23
 None
 1.01A 4z69A-2ys1A:
undetectable		 4z69A-2ys1A:
9.91