SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ys2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_E_CLME221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2ys2	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	3 / 3	PHE A 25 CYH A 27 HIS A 16	None ZN A 201 (-2.2A) ZN A 201 (-3.1A)	1.10A	3u9fF-2ys2A: undetectable	3u9fF-2ys2A: 11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2ys2	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	3 / 3	PHE A 25 CYH A 27 HIS A 16	None ZN A 201 (-2.2A) ZN A 201 (-3.1A)	1.02A	3u9fG-2ys2A: undetectable	3u9fG-2ys2A: 11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_K_CLMK221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2ys2	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	3 / 3	PHE A 25 CYH A 27 HIS A 16	None ZN A 201 (-2.2A) ZN A 201 (-3.1A)	1.08A	3u9fL-2ys2A: undetectable	3u9fL-2ys2A: 11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_R_CLMR221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2ys2	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	3 / 3	PHE A 25 CYH A 27 HIS A 16	None ZN A 201 (-2.2A) ZN A 201 (-3.1A)	1.04A	3u9fS-2ys2A: undetectable	3u9fS-2ys2A: 11.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3U9F_E_CLME221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2ys2","CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX","Homo sapiens",3,"PHE A  25;CYH A  27;HIS A  16","None; ZN A 201 (-2.2A); ZN A 201 (-3.1A)","1.10A","3u9fF-2ys2A:undetectable","3u9fF-2ys2A:11.06"],["3U9F_I_CLMI221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","2ys2","CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX","Homo sapiens",3,"PHE A  25;CYH A  27;HIS A  16","None; ZN A 201 (-2.2A); ZN A 201 (-3.1A)","1.02A","3u9fG-2ys2A:undetectable","3u9fG-2ys2A:11.06"],["3U9F_K_CLMK221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2ys2","CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX","Homo sapiens",3,"PHE A  25;CYH A  27;HIS A  16","None; ZN A 201 (-2.2A); ZN A 201 (-3.1A)","1.08A","3u9fL-2ys2A:undetectable","3u9fL-2ys2A:11.06"],["3U9F_R_CLMR221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2ys2","CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX","Homo sapiens",3,"PHE A  25;CYH A  27;HIS A  16","None; ZN A 201 (-2.2A); ZN A 201 (-3.1A)","1.04A","3u9fS-2ys2A:undetectable","3u9fS-2ys2A:11.06"]]