SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ytv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2ytv COLD SHOCK
DOMAIN-CONTAINING
PROTEIN E1
(Homo
sapiens) 		4 / 6 GLU A  51
ARG A   9
PHE A  54
TYR A  25
 None
 1.41A 4uciA-2ytvA:
undetectable		 4uciA-2ytvA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2ytv COLD SHOCK
DOMAIN-CONTAINING
PROTEIN E1
(Homo
sapiens) 		4 / 7 GLU A  51
ARG A   9
PHE A  54
TYR A  25
 None
 1.40A 4uciB-2ytvA:
undetectable		 4uciB-2ytvA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2ytv COLD SHOCK
DOMAIN-CONTAINING
PROTEIN E1
(Homo
sapiens) 		4 / 9 PHE A  22
HIS A  36
VAL A  73
SER A  74
 None
 1.00A 6c2mD-2ytvA:
undetectable		 6c2mD-2ytvA:
27.17