SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2yue PROTEIN NEURALIZED
(Drosophila
melanogaster) 		4 / 7 VAL A 122
GLY A 120
THR A 140
ILE A 138
 None
 0.87A 1gtnC-2yueA:
undetectable
1gtnD-2yueA:
undetectable		 1gtnC-2yueA:
16.67
1gtnD-2yueA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2yue PROTEIN NEURALIZED
(Drosophila
melanogaster) 		5 / 11 ALA A  37
CYH A 154
GLY A 152
ILE A  66
VAL A  53
 None
 1.04A 2uxpB-2yueA:
undetectable		 2uxpB-2yueA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2yue PROTEIN NEURALIZED
(Drosophila
melanogaster) 		4 / 4 GLY A  25
GLU A 158
ASP A 161
ASP A  24
 None
 1.38A 3mb5A-2yueA:
undetectable		 3mb5A-2yueA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 2yue PROTEIN NEURALIZED
(Drosophila
melanogaster) 		4 / 4 ASN A 117
ALA A 119
GLY A 120
THR A 136
 None
 1.09A 4bboC-2yueA:
undetectable		 4bboC-2yueA:
20.12