SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		4 / 7 CYH A 148
THR A 150
SER A 178
LEU A  99
 None
 1.02A 1qcaA-2yujA:
undetectable		 1qcaA-2yujA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		5 / 12 TYR A  60
GLY A  78
ILE A 179
SER A 178
ARG A 144
 None
 1.03A 1ve3B-2yujA:
undetectable		 1ve3B-2yujA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		3 / 3 LEU A  50
PHE A  82
ARG A  15
 None
 0.71A 1xdkB-2yujA:
undetectable		 1xdkB-2yujA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		3 / 3 LEU A  50
PHE A  82
ARG A  15
 None
 0.71A 1xdkF-2yujA:
undetectable		 1xdkF-2yujA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		3 / 3 PRO A  61
ASN A 113
ARG A  15
 None
 0.90A 2qeuB-2yujA:
undetectable		 2qeuB-2yujA:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		4 / 8 SER A 178
PHE A  16
ASN A 113
ILE A  58
 None
 0.95A 3aodA-2yujA:
undetectable		 3aodA-2yujA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE
(Homo
sapiens) 		5 / 12 LEU A 114
GLY A  78
GLY A  41
PRO A  92
LEU A  91
 None
 1.32A 4x61A-2yujA:
undetectable		 4x61A-2yujA:
15.80