SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		4 / 6 ASP A  49
GLY A 110
PRO A  21
ILE A  23
 None
 0.83A 1n49D-2yv7A:
undetectable		 1n49D-2yv7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 12 LEU A 204
LEU A 201
ILE A 197
ILE A 185
LEU A 147
 None
 1.05A 2bdmA-2yv7A:
undetectable		 2bdmA-2yv7A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 12 LEU A 132
LEU A 147
ILE A 227
LEU A 201
PRO A 198
 None
 1.15A 2hrcA-2yv7A:
undetectable		 2hrcA-2yv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 12 LEU A 132
LEU A 147
ILE A 227
LEU A 201
PRO A 198
 None
 1.20A 2hrcB-2yv7A:
undetectable		 2hrcB-2yv7A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 12 LEU A  52
CYH A 176
GLY A 168
CYH A 172
LEU A 114
 None
 1.37A 3okxA-2yv7A:
undetectable		 3okxA-2yv7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 11 ALA A 203
LEU A 204
TYR A 207
LEU A 151
LEU A 182
 None
 0.96A 4wg0C-2yv7A:
undetectable
4wg0D-2yv7A:
undetectable
4wg0E-2yv7A:
undetectable		 4wg0C-2yv7A:
4.65
4wg0D-2yv7A:
4.65
4wg0E-2yv7A:
4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 11 ALA A 203
LEU A 204
TYR A 207
LEU A 151
LEU A 182
 None
 0.96A 4wg0E-2yv7A:
undetectable
4wg0F-2yv7A:
undetectable
4wg0G-2yv7A:
undetectable		 4wg0E-2yv7A:
4.65
4wg0F-2yv7A:
4.65
4wg0G-2yv7A:
4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 2yv7 CG10997-PA
(Drosophila
melanogaster) 		5 / 12 LEU A 128
LEU A 178
ILE A 197
LEU A 147
MET A 208
 None
 1.16A 5og9B-2yv7A:
undetectable		 5og9B-2yv7A:
19.74