SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2yvi ANKYRIN-1
(Homo
sapiens) 		4 / 7 LEU A1454
LEU A1451
SER A1448
VAL A1438
 None
 0.88A 3d2tA-2yviA:
undetectable		 3d2tA-2yviA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2yvi ANKYRIN-1
(Homo
sapiens) 		5 / 10 ILE A1480
PHE A1428
ALA A1450
LEU A1451
ALA A1423
 None
 1.31A 3lw5B-2yviA:
undetectable		 3lw5B-2yviA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2yvi ANKYRIN-1
(Homo
sapiens) 		5 / 12 SER A1443
LEU A1445
VAL A1449
ALA A1450
LEU A1451
 None
 0.91A 5kpcA-2yviA:
undetectable		 5kpcA-2yviA:
12.15