SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		4 / 6 ALA A  78
TRP A  76
ILE A 106
ILE A 112
 None
 1.12A 2dcfA-2yvuA:
undetectable		 2dcfA-2yvuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		4 / 7 ALA A  78
TRP A  76
ILE A 106
ILE A 112
 None
 1.12A 2zm7A-2yvuA:
undetectable		 2zm7A-2yvuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		5 / 12 VAL A 181
TYR A 176
TYR A 178
ASN A 168
SER A  24
 None
 1.46A 2zthA-2yvuA:
undetectable		 2zthA-2yvuA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		3 / 3 GLY A  23
GLY A  25
THR A  27
 None
 0.46A 3si7B-2yvuA:
3.4		 3si7B-2yvuA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		5 / 12 PRO A 113
ILE A  14
TYR A  42
VAL A  44
ILE A  10
 None
 1.48A 4xe0A-2yvuA:
undetectable		 4xe0A-2yvuA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2yvu PROBABLE
ADENYLYL-SULFATE
KINASE
(Aeropyrum
pernix) 		6 / 12 THR A  31
LEU A  33
ALA A  30
LEU A  18
LEU A 163
GLY A  23
 None
 1.16A 4xi3C-2yvuA:
undetectable		 4xi3C-2yvuA:
22.80