SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ywj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		4 / 8 LEU A  92
THR A  85
LEU A  94
VAL A  99
 None
 0.93A 1sn5C-2ywjA:
undetectable		 1sn5C-2ywjA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  73
GLY A  45
GLY A  77
 None
 0.37A 3bogC-2ywjA:
undetectable		 3bogC-2ywjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		3 / 3 LEU A  81
MET A  95
ASP A  39
 None
 0.73A 4j7xB-2ywjA:
2.4		 4j7xB-2ywjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A  92
ALA A   7
ILE A   8
ILE A  38
LEU A  35
 None
 0.96A 4r3aB-2ywjA:
undetectable		 4r3aB-2ywjA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		4 / 4 LEU A  61
ILE A  64
GLY A  52
ILE A  43
 None
 0.90A 5dzk3-2ywjA:
undetectable
5dzkm-2ywjA:
undetectable		 5dzk3-2ywjA:
3.28
5dzkm-2ywjA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		4 / 8 GLU A  93
GLY A  52
THR A  74
TYR A 159
 None
 0.99A 5flcB-2ywjA:
undetectable		 5flcB-2ywjA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2ywj GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Methanocaldococc
us
jannaschii) 		4 / 8 GLU A  93
GLY A  52
THR A  74
TYR A 159
 None
 0.99A 5flcF-2ywjA:
undetectable		 5flcF-2ywjA:
9.91