SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ywm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		4 / 5 GLU A 125
LEU A 131
LEU A 128
LEU A 130
 None
 1.01A 1np1A-2ywmA:
undetectable		 1np1A-2ywmA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 PHE A 185
VAL A 194
TRP A 141
 None
 0.89A 2cc8A-2ywmA:
undetectable		 2cc8A-2ywmA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 PHE A 185
VAL A 194
TRP A 141
 None
 0.90A 2ccbA-2ywmA:
undetectable		 2ccbA-2ywmA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 TRP A 159
ALA A 154
VAL A 156
 None
 0.81A 2izqA-2ywmA:
undetectable
2izqB-2ywmA:
undetectable		 2izqA-2ywmA:
5.23
2izqB-2ywmA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 PHE A 185
VAL A 194
TRP A 141
 None
 0.89A 2vx9A-2ywmA:
undetectable		 2vx9A-2ywmA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 ALA A 154
VAL A 156
TRP A 159
 None
 0.82A 3l8lA-2ywmA:
undetectable
3l8lB-2ywmA:
undetectable		 3l8lA-2ywmA:
5.23
3l8lB-2ywmA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		4 / 8 VAL A 172
GLY A 112
ILE A 113
PRO A 101
 None
 0.64A 3nu9A-2ywmA:
undetectable		 3nu9A-2ywmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		5 / 12 LEU A 109
ILE A  51
LEU A  11
ILE A  87
ILE A  25
 None
 0.99A 4odrA-2ywmA:
undetectable
4odrB-2ywmA:
undetectable		 4odrA-2ywmA:
19.65
4odrB-2ywmA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		4 / 8 ILE A  60
LYS A  59
ILE A  51
ALA A  15
 None
 0.92A 4ou1A-2ywmA:
undetectable		 4ou1A-2ywmA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		5 / 12 LEU A  14
ILE A 110
LEU A 109
ILE A 113
ILE A  51
 None
 0.86A 4y0rA-2ywmA:
undetectable		 4y0rA-2ywmA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 THR A 146
PRO A  83
ARG A  81
 None
 0.83A 5nd7B-2ywmA:
undetectable		 5nd7B-2ywmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1S_A_SAMA604_0
(RADICAL SAM)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		5 / 9 LEU A 123
GLU A 125
THR A 127
VAL A 134
TYR A 167
 None
 1.37A 5v1sA-2ywmA:
0.2		 5v1sA-2ywmA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 LEU A 181
GLN A 184
LYS A 171
 None
 0.94A 6exiB-2ywmA:
undetectable		 6exiB-2ywmA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2ywm GLUTAREDOXIN-LIKE
PROTEIN
(Aquifex
aeolicus) 		3 / 3 LEU A 181
GLN A 184
LYS A 171
 None
 0.97A 6exiA-2ywmA:
undetectable		 6exiA-2ywmA:
14.09