SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ywn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A  40
SER A  69
PHE A  79
ALA A  38
 None
 1.17A 1fxvA-2ywnA:
undetectable
1fxvB-2ywnA:
undetectable		 1fxvA-2ywnA:
19.91
1fxvB-2ywnA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A  65
VAL A 150
ILE A 123
ARG A 118
 None
 0.98A 3mssB-2ywnA:
undetectable		 3mssB-2ywnA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A  10
LEU A  26
LEU A  66
ILE A  68
LEU A  33
 None
 1.06A 4odoA-2ywnA:
undetectable		 4odoA-2ywnA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A  10
LEU A  26
LEU A  66
ILE A  68
LEU A  33
 None
 1.09A 4odoB-2ywnA:
undetectable		 4odoB-2ywnA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A  10
LEU A  26
LEU A  66
ILE A  68
LEU A  33
 None
 1.06A 4odoC-2ywnA:
undetectable		 4odoC-2ywnA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2ywn PEROXIREDOXIN-LIKE
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 11 ASP A  10
LEU A  26
LEU A  66
ILE A  68
LEU A  33
 None
 0.95A 4odrA-2ywnA:
undetectable
4odrB-2ywnA:
undetectable		 4odrA-2ywnA:
19.38
4odrB-2ywnA:
19.38