SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ywq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		4 / 7 VAL A  84
LEU A  42
TYR A  20
LEU A  25
 None
 0.88A 1cqpA-2ywqA:
undetectable
1cqpB-2ywqA:
undetectable		 1cqpA-2ywqA:
21.20
1cqpB-2ywqA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		4 / 8 ARG A  68
LEU A  42
LEU A  25
ILE A  13
 None
 0.69A 3ln1A-2ywqA:
undetectable		 3ln1A-2ywqA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		4 / 7 ARG A  68
LEU A  42
LEU A  25
ILE A  13
 None
 0.69A 3ln1B-2ywqA:
undetectable		 3ln1B-2ywqA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		3 / 3 TYR A   4
LYS A   5
LYS A  39
 None
 1.35A 5dbyA-2ywqA:
undetectable		 5dbyA-2ywqA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		3 / 3 THR A  14
ASP A  15
ALA A  16
 None
 0.02A 5g5gB-2ywqA:
undetectable		 5g5gB-2ywqA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		5 / 12 ILE A   3
ASP A  29
VAL A  60
LEU A   6
LEU A  42
 None
 1.21A 6b54A-2ywqA:
undetectable		 6b54A-2ywqA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2ywq RIBOSOMAL SUBUNIT
INTERFACE PROTEIN
(Thermus
thermophilus) 		6 / 12 MET A   1
ILE A   3
ASP A  29
LEU A  36
LEU A   6
LEU A  42
 None
 1.48A 6b54A-2ywqA:
undetectable		 6b54A-2ywqA:
18.83