SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ywv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		5 / 9 LEU A 179
PHE A 177
LEU A 191
LEU A  62
ALA A 158
 None
 1.20A 2bxeA-2ywvA:
undetectable		 2bxeA-2ywvA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		5 / 9 LEU A 191
PHE A 181
LEU A  62
LEU A 163
ALA A 158
 None
 1.37A 2bxeA-2ywvA:
undetectable		 2bxeA-2ywvA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 4 GLU A 120
ARG A  95
ASN A  96
ASP A 176
 None
SO4  A 543 (-3.3A)
None
SO4  A 543 ( 4.6A)
 1.47A 2zq9A-2ywvA:
undetectable		 2zq9A-2ywvA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		5 / 12 ILE A 189
ALA A 151
LEU A 152
ALA A 150
VAL A  85
 None
None
None
None
ADP  A 600 (-4.0A)
 1.13A 3dzyA-2ywvA:
undetectable		 3dzyA-2ywvA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		3 / 3 THR A  34
ASP A 126
GLU A  91
 None
 0.86A 3qowA-2ywvA:
undetectable		 3qowA-2ywvA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 7 GLY A 111
ARG A 173
ALA A  99
ILE A 175
 None
SO4  A 545 (-4.0A)
None
None
 0.94A 4txnA-2ywvA:
undetectable		 4txnA-2ywvA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 7 GLY A 111
ARG A 173
ALA A  99
ILE A 175
 None
SO4  A 545 (-4.0A)
None
None
 0.95A 4txnC-2ywvA:
undetectable		 4txnC-2ywvA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 7 ASP A 176
ILE A 175
GLY A 111
TRP A 203
 SO4  A 543 ( 4.6A)
None
None
None
 0.93A 4zxiA-2ywvA:
undetectable		 4zxiA-2ywvA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 5 GLU A 194
LYS A  14
ASP A 193
GLU A 180
 None
ADP  A 600 (-2.7A)
ADP  A 600 ( 3.5A)
ADP  A 600 (-3.3A)
 1.35A 5a06A-2ywvA:
undetectable		 5a06A-2ywvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 7 ARG A 218
ARG A  95
ASP A 176
ILE A 175
 None
SO4  A 543 (-3.3A)
SO4  A 543 ( 4.6A)
None
 0.99A 5a06B-2ywvA:
undetectable		 5a06B-2ywvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 4 LEU A  58
ILE A 195
PRO A 197
LEU A 202
 None
 1.22A 5eb3A-2ywvA:
undetectable		 5eb3A-2ywvA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		3 / 3 TRP A 203
GLU A 110
ASP A 176
 None
None
SO4  A 543 ( 4.6A)
 1.05A 5gqbA-2ywvA:
undetectable		 5gqbA-2ywvA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE
(Geobacillus
kaustophilus) 		4 / 8 ALA A 156
VAL A 159
PHE A  59
LEU A  62
 None
 0.84A 5nujA-2ywvA:
undetectable		 5nujA-2ywvA:
17.39