SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		3 / 3 GLU A  38
GLU A  47
LEU A  65
 None
 0.74A 1v8bA-2yxmA:
undetectable		 1v8bA-2yxmA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		3 / 3 VAL A  26
TYR A  18
GLN A  19
 None
 0.55A 5qgkA-2yxmA:
undetectable		 5qgkA-2yxmA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		3 / 3 VAL A  26
TYR A  18
GLN A  19
 None
 0.51A 5qgrA-2yxmA:
undetectable		 5qgrA-2yxmA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		3 / 3 VAL A  26
TYR A  18
GLN A  19
 None
 0.58A 5qgtA-2yxmA:
undetectable		 5qgtA-2yxmA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		4 / 8 ILE A  64
GLN A  62
VAL A  30
THR A  89
 None
 0.84A 6cduD-2yxmA:
undetectable
6cduE-2yxmA:
undetectable		 6cduD-2yxmA:
14.80
6cduE-2yxmA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		4 / 7 THR A  89
ILE A  64
GLN A  62
VAL A  30
 None
 0.79A 6cduF-2yxmA:
1.9
6cduJ-2yxmA:
undetectable		 6cduF-2yxmA:
14.80
6cduJ-2yxmA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2yxm MYOSIN-BINDING
PROTEIN C, SLOW-TYPE
(Homo
sapiens) 		4 / 7 ILE A  64
GLN A  62
VAL A  30
THR A  89
 None
 0.83A 6cduF-2yxmA:
2.1
6cduG-2yxmA:
undetectable		 6cduF-2yxmA:
14.80
6cduG-2yxmA:
14.80