SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2yy9 ZINC FINGER AND BTB
DOMAIN-CONTAINING
PROTEIN 48
(Mus
musculus) 		5 / 12 ALA A  39
GLY A  74
VAL A  32
LEU A  65
LEU A  44
 None
 1.21A 1jipA-2yy9A:
undetectable		 1jipA-2yy9A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2yy9 ZINC FINGER AND BTB
DOMAIN-CONTAINING
PROTEIN 48
(Mus
musculus) 		4 / 5 LEU A  44
PHE A  73
VAL A  63
ALA A  28
 None
 1.11A 2cizA-2yy9A:
undetectable		 2cizA-2yy9A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2yy9 ZINC FINGER AND BTB
DOMAIN-CONTAINING
PROTEIN 48
(Mus
musculus) 		5 / 12 LEU A  30
GLY A  68
LEU A  97
GLU A 101
LEU A 102
 None
 1.23A 4x61A-2yy9A:
undetectable		 4x61A-2yy9A:
11.92