SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2yz1 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE
SUBSTRATE 1
(Mus
musculus) 		5 / 12 GLY A 101
PHE A  98
GLY A  38
SER A 111
ASP A 106
 None
 1.13A 4rtsA-2yz1A:
undetectable		 4rtsA-2yz1A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 2yz1 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE
SUBSTRATE 1
(Mus
musculus) 		5 / 10 ALA A  21
VAL A  19
ASP A  23
SER A  83
GLY A  22
 None
 1.39A 4xp1A-2yz1A:
undetectable		 4xp1A-2yz1A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 2yz1 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE
SUBSTRATE 1
(Mus
musculus) 		3 / 3 GLU A  59
HIS A  60
VAL A  64
 None
 0.84A 5trqB-2yz1A:
undetectable		 5trqB-2yz1A:
15.99