SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 10 PRO A  54
THR A  58
CYH A  61
LEU A 126
ARG A 132
None
0.77A 1h4oA-2yzhA:
19.1
1h4oB-2yzhA:
19.1
1h4oA-2yzhA:
24.19
1h4oB-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 10 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
None
0.40A 1h4oA-2yzhA:
19.1
1h4oB-2yzhA:
19.1
1h4oA-2yzhA:
24.19
1h4oB-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 10 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.74A 1h4oA-2yzhA:
19.1
1h4oB-2yzhA:
19.1
1h4oA-2yzhA:
24.19
1h4oB-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
None
0.46A 1h4oB-2yzhA:
19.1
1h4oB-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.77A 1h4oB-2yzhA:
19.1
1h4oB-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
None
0.45A 1h4oC-2yzhA:
19.0
1h4oD-2yzhA:
19.1
1h4oC-2yzhA:
24.19
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.76A 1h4oC-2yzhA:
19.0
1h4oD-2yzhA:
19.1
1h4oC-2yzhA:
24.19
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.99A 1h4oD-2yzhA:
19.1
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.72A 1h4oD-2yzhA:
19.1
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
None
0.46A 1h4oE-2yzhA:
19.1
1h4oF-2yzhA:
19.1
1h4oE-2yzhA:
24.19
1h4oF-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.74A 1h4oE-2yzhA:
19.1
1h4oF-2yzhA:
19.1
1h4oE-2yzhA:
24.19
1h4oF-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.98A 1h4oF-2yzhA:
19.1
1h4oF-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.74A 1h4oF-2yzhA:
19.1
1h4oF-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 8 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.92A 1h4oG-2yzhA:
19.0
1h4oG-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.91A 1h4oH-2yzhA:
19.0
1h4oH-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.74A 1h4oH-2yzhA:
19.0
1h4oH-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.93A 1hd2A-2yzhA:
19.2
1hd2A-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.76A 1hd2A-2yzhA:
19.2
1hd2A-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
None
0.45A 1oc3A-2yzhA:
19.2
1oc3A-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.71A 1oc3A-2yzhA:
19.2
1oc3A-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 9 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.95A 1oc3B-2yzhA:
18.8
1oc3B-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.73A 1oc3B-2yzhA:
18.8
1oc3B-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 12 THR A  52
PRO A  54
ILE A 152
VAL A   5
LEU A  14
None
1.20A 1z9hD-2yzhA:
1.7
1z9hD-2yzhA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.67A 2v2gA-2yzhA:
15.8
2v2gB-2yzhA:
15.8
2v2gA-2yzhA:
25.43
2v2gB-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.63A 2v2gA-2yzhA:
15.8
2v2gB-2yzhA:
15.8
2v2gA-2yzhA:
25.43
2v2gB-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.65A 2v2gC-2yzhA:
15.8
2v2gD-2yzhA:
15.9
2v2gC-2yzhA:
25.43
2v2gD-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.65A 2v2gC-2yzhA:
15.8
2v2gD-2yzhA:
15.9
2v2gC-2yzhA:
25.43
2v2gD-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 8 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.58A 2v32A-2yzhA:
15.7
2v32B-2yzhA:
15.7
2v32A-2yzhA:
25.43
2v32B-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 8 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.63A 2v32A-2yzhA:
15.7
2v32B-2yzhA:
15.7
2v32A-2yzhA:
25.43
2v32B-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.60A 2v32C-2yzhA:
15.7
2v32D-2yzhA:
17.5
2v32C-2yzhA:
25.43
2v32D-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 8 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.66A 2v32C-2yzhA:
15.7
2v32D-2yzhA:
17.5
2v32C-2yzhA:
25.43
2v32D-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.59A 2v41A-2yzhA:
15.7
2v41B-2yzhA:
15.9
2v41A-2yzhA:
25.43
2v41B-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 9 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.62A 2v41A-2yzhA:
15.7
2v41B-2yzhA:
15.9
2v41A-2yzhA:
25.43
2v41B-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.65A 2v41C-2yzhA:
17.4
2v41D-2yzhA:
17.6
2v41C-2yzhA:
25.43
2v41D-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.63A 2v41C-2yzhA:
17.4
2v41D-2yzhA:
17.6
2v41C-2yzhA:
25.43
2v41D-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.56A 2v41E-2yzhA:
15.7
2v41F-2yzhA:
15.6
2v41E-2yzhA:
25.43
2v41F-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 7 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.62A 2v41E-2yzhA:
15.7
2v41F-2yzhA:
15.6
2v41E-2yzhA:
25.43
2v41F-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
4 / 8 THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.62A 2v41G-2yzhA:
15.7
2v41H-2yzhA:
15.7
2v41G-2yzhA:
25.43
2v41H-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 8 PRO A  54
THR A  58
PRO A  59
VAL A  60
ARG A 132
None
0.58A 2v41G-2yzhA:
15.7
2v41H-2yzhA:
15.7
2v41G-2yzhA:
25.43
2v41H-2yzhA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 10 PRO A  54
THR A  58
PRO A  59
CYH A  61
LEU A 126
ARG A 132
None
0.98A 2vl2A-2yzhA:
19.2
2vl2C-2yzhA:
16.5
2vl2A-2yzhA:
23.28
2vl2C-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 10 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
None
0.69A 2vl2A-2yzhA:
19.2
2vl2C-2yzhA:
16.5
2vl2A-2yzhA:
23.28
2vl2C-2yzhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
6 / 12 ASP A 113
ASP A 108
VAL A  83
GLY A  41
THR A  81
THR A 104
None
1.36A 3el5B-2yzhA:
undetectable
3el5B-2yzhA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 12 ASP A 113
ASP A 108
VAL A  83
GLY A  41
THR A 104
None
1.02A 4njuA-2yzhA:
undetectable
4njuA-2yzhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 12 ASP A 113
ASP A 108
VAL A  83
GLY A  41
THR A 104
None
1.05A 4njuC-2yzhA:
undetectable
4njuC-2yzhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WHY_B_SAMB504_0
(RADICAL SAM DOMAIN
PROTEIN)
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus)
5 / 10 TYR A 145
GLU A  64
THR A  52
VAL A  21
VAL A 143
None
1.42A 5whyB-2yzhA:
0.6
5whyB-2yzhA:
15.40