SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 2yzj 167AA LONG
HYPOTHETICAL DUTPASE
(Sulfurisphaera
tokodaii) 		4 / 6 ASN A 124
PHE A  81
ALA A 126
THR A  78
 None
 1.05A 3t3sB-2yzjA:
undetectable		 3t3sB-2yzjA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 2yzj 167AA LONG
HYPOTHETICAL DUTPASE
(Sulfurisphaera
tokodaii) 		4 / 6 THR A 102
ASN A 106
GLY A 107
ILE A 127
 None
 0.79A 3w9tF-2yzjA:
undetectable		 3w9tF-2yzjA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2yzj 167AA LONG
HYPOTHETICAL DUTPASE
(Sulfurisphaera
tokodaii) 		3 / 3 ASN A 124
LEU A 144
PHE A  81
 None
 0.77A 4dajB-2yzjA:
undetectable		 4dajB-2yzjA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 2yzj 167AA LONG
HYPOTHETICAL DUTPASE
(Sulfurisphaera
tokodaii) 		3 / 3 ARG A  63
TYR A  79
GLU A  48
 None
 0.69A 4zzbE-2yzjA:
undetectable		 4zzbE-2yzjA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 2yzj 167AA LONG
HYPOTHETICAL DUTPASE
(Sulfurisphaera
tokodaii) 		5 / 12 MET A 139
ILE A  41
ALA A 129
SER A 133
ILE A 127
 None
 1.39A 5mlmA-2yzjA:
undetectable		 5mlmA-2yzjA:
18.29