SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 9 GLU A  64
LEU A  48
ALA A  51
LEU A  52
LEU A  61
MES  A 301 (-3.4A)
None
None
None
None
1.23A 1hwiA-2z0jA:
undetectable
1hwiA-2z0jA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 11 ARG A 129
LEU A 162
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
1.48A 1hxwB-2z0jA:
undetectable
1hxwB-2z0jA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 10 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.11A 2aquA-2z0jA:
undetectable
2aquA-2z0jA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 11 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.15A 2aquB-2z0jA:
undetectable
2aquB-2z0jA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 8 ALA A  82
GLU A  81
LEU A  61
VAL A  60
None
0.91A 2bxgA-2z0jA:
undetectable
2bxgA-2z0jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.06A 2f162-2z0jA:
undetectable
2f162-2z0jA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.05A 2f16N-2z0jA:
undetectable
2f16N-2z0jA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.21A 2fxeA-2z0jA:
undetectable
2fxeA-2z0jA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
LEU A 162
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
1.47A 2ieoA-2z0jA:
undetectable
2ieoA-2z0jA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.21A 2o4kB-2z0jA:
undetectable
2o4kB-2z0jA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.20A 2o4lB-2z0jA:
undetectable
2o4lB-2z0jA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
3 / 3 LEU A 188
PRO A 187
LEU A 191
None
0.50A 2po5B-2z0jA:
2.9
2po5B-2z0jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
3 / 3 LEU A 188
PRO A 187
LEU A 191
None
0.53A 2po7B-2z0jA:
2.8
2po7B-2z0jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 7 PRO A 222
ALA A  31
LEU A  35
ALA A  39
None
1.13A 2vcvA-2z0jA:
undetectable
2vcvA-2z0jA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 7 HIS A 112
LEU A 114
LEU A 131
LEU A 127
None
0.93A 3bgdB-2z0jA:
undetectable
3bgdB-2z0jA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 THR A  96
VAL A  22
ALA A 103
ILE A  25
THR A 154
None
1.28A 3dl9B-2z0jA:
undetectable
3dl9B-2z0jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
0.93A 3ekyA-2z0jA:
undetectable
3ekyA-2z0jA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 9 ARG A 129
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.19A 3em4B-2z0jA:
undetectable
3em4B-2z0jA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 11 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.08A 3em4U-2z0jA:
undetectable
3em4U-2z0jA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 5 ASN A 120
ALA A  32
ALA A 220
ARG A 236
None
1.47A 3kp2B-2z0jA:
undetectable
3kp2B-2z0jA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 5 ASN A 120
ALA A 124
ALA A 123
ARG A 126
None
0.91A 3kp2B-2z0jA:
undetectable
3kp2B-2z0jA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA206_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 4 ASP A  23
ARG A  26
THR A  30
ALA A  27
CA  A 401 (-3.0A)
MES  A 301 (-3.7A)
None
MES  A 301 (-4.6A)
1.28A 3mbgA-2z0jA:
0.0
3mbgA-2z0jA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 7 ASP A  23
ARG A  26
THR A  30
ALA A  27
CA  A 401 (-3.0A)
MES  A 301 (-3.7A)
None
MES  A 301 (-4.6A)
1.30A 3mbgA-2z0jA:
undetectable
3mbgB-2z0jA:
undetectable
3mbgA-2z0jA:
18.99
3mbgB-2z0jA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.04A 3mg02-2z0jA:
undetectable
3mg0V-2z0jA:
undetectable
3mg02-2z0jA:
21.26
3mg0V-2z0jA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.05A 3mg0N-2z0jA:
undetectable
3mg0N-2z0jA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
0.86A 3ndxB-2z0jA:
undetectable
3ndxB-2z0jA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 8 LEU A  48
ALA A 231
THR A  45
GLY A  76
PRO A  70
None
1.47A 3ny4A-2z0jA:
undetectable
3ny4A-2z0jA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 8 ASN A  98
ASP A 150
SER A 194
ASP A 151
None
CA  A 401 ( 4.8A)
None
CA  A 401 ( 4.4A)
1.12A 3sg9B-2z0jA:
undetectable
3sg9B-2z0jA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
LEU A 162
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
1.49A 3tkgB-2z0jA:
undetectable
3tkgB-2z0jA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
GLY A 156
ALA A 155
GLY A 173
VAL A 136
ILE A 138
None
1.16A 3tl9B-2z0jA:
undetectable
3tl9B-2z0jA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
LEU A 162
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
1.49A 3tl9B-2z0jA:
undetectable
3tl9B-2z0jA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 8 SER A  78
ALA A  32
LEU A  83
THR A  29
None
0.85A 4ikjA-2z0jA:
undetectable
4ikjB-2z0jA:
undetectable
4ikjA-2z0jA:
19.40
4ikjB-2z0jA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
4 / 8 SER A  78
ALA A  32
LEU A  83
THR A  29
None
0.82A 4iklA-2z0jA:
undetectable
4iklB-2z0jA:
undetectable
4iklA-2z0jA:
19.40
4iklB-2z0jA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 ALA A 159
ILE A 138
VAL A  22
ALA A 121
ALA A 125
None
1.07A 4lbgA-2z0jA:
undetectable
4lbgA-2z0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 9 ALA A 159
ILE A 138
VAL A  22
ALA A 121
ALA A 125
None
1.00A 4lbgB-2z0jA:
undetectable
4lbgB-2z0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 ALA A  33
ALA A  32
LEU A  83
ALA A  82
HIS A 122
None
1.06A 4nqaH-2z0jA:
undetectable
4nqaH-2z0jA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 GLU A  36
ARG A 236
ASN A 120
ALA A 123
LEU A 127
None
1.25A 4oadA-2z0jA:
undetectable
4oadA-2z0jA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 9 VAL A  22
VAL A 215
ALA A 216
VAL A 221
ALA A 116
None
1.32A 4oqrA-2z0jA:
undetectable
4oqrA-2z0jA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 PHE A  73
THR A  97
SER A  95
ASP A  23
GLY A  66
None
MES  A 301 (-3.7A)
None
CA  A 401 (-3.0A)
MES  A 301 (-3.4A)
1.47A 4qb9E-2z0jA:
undetectable
4qb9E-2z0jA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.47A 4qvlV-2z0jA:
undetectable
4qvlW-2z0jA:
0.0
4qvlV-2z0jA:
23.37
4qvlW-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.47A 4qvwH-2z0jA:
undetectable
4qvwI-2z0jA:
undetectable
4qvwH-2z0jA:
23.37
4qvwI-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.47A 4qvwV-2z0jA:
undetectable
4qvwW-2z0jA:
undetectable
4qvwV-2z0jA:
23.37
4qvwW-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 10 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.45A 4qw3H-2z0jA:
0.0
4qw3I-2z0jA:
0.0
4qw3H-2z0jA:
23.37
4qw3I-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.45A 4qw3V-2z0jA:
undetectable
4qw3W-2z0jA:
undetectable
4qw3V-2z0jA:
23.37
4qw3W-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 11 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.48A 5cz7H-2z0jA:
undetectable
5cz7I-2z0jA:
0.0
5cz7H-2z0jA:
23.37
5cz7I-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 SER A 218
GLN A 214
ALA A 116
THR A  29
ALA A  32
None
1.47A 5d0xH-2z0jA:
undetectable
5d0xI-2z0jA:
undetectable
5d0xH-2z0jA:
23.37
5d0xI-2z0jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 ALA A  51
PRO A  70
PHE A  73
SER A  78
SER A  95
None
1.31A 5hfjF-2z0jA:
undetectable
5hfjF-2z0jA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 VAL A  24
SER A 117
ALA A 125
VAL A 157
LEU A 191
None
1.12A 5kirB-2z0jA:
undetectable
5kirB-2z0jA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.05A 5lf7V-2z0jA:
undetectable
5lf7b-2z0jA:
undetectable
5lf7V-2z0jA:
22.43
5lf7b-2z0jA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
5 / 12 THR A 100
THR A  28
THR A  29
ALA A  32
SER A  95
None
1.04A 5lf7H-2z0jA:
undetectable
5lf7N-2z0jA:
undetectable
5lf7H-2z0jA:
22.43
5lf7N-2z0jA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus)
6 / 12 ARG A 129
LEU A 162
GLY A 156
ALA A 155
GLY A 173
VAL A 136
None
1.43A 6dilB-2z0jA:
undetectable
6dilB-2z0jA:
15.25