SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A  79
ASP A  82
ASP A  56
 None
 0.81A 2ejtA-2z0uA:
undetectable		 2ejtA-2z0uA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A  25
ILE A 128
LEU A 130
VAL A  63
PHE A  38
 None
 1.21A 2qo5A-2z0uA:
undetectable		 2qo5A-2z0uA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 LYS A  30
ALA A  39
SER A  96
VAL A  92
 None
 0.95A 3d2tA-2z0uA:
undetectable		 3d2tA-2z0uA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 LYS A  30
ALA A  39
SER A  96
VAL A  92
 None
 0.92A 3d2tB-2z0uA:
undetectable		 3d2tB-2z0uA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A  25
ILE A  61
VAL A  63
VAL A  65
LEU A 130
 None
 1.10A 4y0pA-2z0uA:
undetectable		 4y0pA-2z0uA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A  27
ILE A  61
VAL A  63
VAL A  65
LEU A 130
 None
 0.82A 4y0pA-2z0uA:
undetectable		 4y0pA-2z0uA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2z0u WW DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		6 / 12 LEU A  29
ILE A  27
ILE A  61
VAL A  63
VAL A  65
LEU A 130
 None
 0.87A 4y0sA-2z0uA:
undetectable		 4y0sA-2z0uA:
21.47