SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 8 VAL A  52
ILE A  73
TYR A  84
PHE A 102
 None
 0.94A 2weyB-2z13A:
undetectable		 2weyB-2z13A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 8 GLU A  23
GLU A  25
PHE A 102
ILE A 104
 None
 0.85A 3jz0B-2z13A:
undetectable		 3jz0B-2z13A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 5 SER A  17
PRO A  45
TYR A  44
VAL A  86
 None
 1.30A 3sufC-2z13A:
undetectable		 3sufC-2z13A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 6 GLU A  24
TYR A  38
GLU A  54
GLU A  56
 None
 1.29A 4mi4A-2z13A:
undetectable		 4mi4A-2z13A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 7 GLU A  24
TYR A  38
GLU A  54
GLU A  56
 None
 1.29A 4mi4A-2z13A:
undetectable
4mi4C-2z13A:
undetectable		 4mi4A-2z13A:
23.12
4mi4C-2z13A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2
(Homo
sapiens) 		4 / 7 GLU A  24
TYR A  38
GLU A  54
GLU A  56
 None
 1.33A 4mj8C-2z13A:
undetectable		 4mj8C-2z13A:
22.35