SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		5 / 12 GLY A 257
ALA A 258
GLY A 227
THR A 192
VAL A 145
 None
 0.94A 3el4A-2z1nA:
undetectable		 3el4A-2z1nA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		5 / 11 ILE A 247
ALA A 250
GLY A 249
GLY A 143
ASN A 183
 None
 1.12A 5ayfA-2z1nA:
undetectable		 5ayfA-2z1nA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		4 / 7 SER A  17
ASP A  66
ARG A  68
GLU A 111
 None
 0.93A 5btaA-2z1nA:
undetectable
5btaC-2z1nA:
undetectable
5btaD-2z1nA:
2.0		 5btaA-2z1nA:
22.76
5btaC-2z1nA:
22.76
5btaD-2z1nA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		4 / 7 SER A  17
ASP A  66
ARG A  68
GLU A 111
 None
 0.92A 5btfA-2z1nA:
undetectable
5btfB-2z1nA:
2.9
5btfC-2z1nA:
undetectable		 5btfA-2z1nA:
22.76
5btfB-2z1nA:
23.49
5btfC-2z1nA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		4 / 7 SER A  16
ASP A  66
ARG A  68
GLU A 111
 None
 1.11A 5btfA-2z1nA:
undetectable
5btfC-2z1nA:
undetectable
5btfD-2z1nA:
1.9		 5btfA-2z1nA:
22.76
5btfC-2z1nA:
22.76
5btfD-2z1nA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2z1n DEHYDROGENASE
(Aeropyrum
pernix) 		4 / 7 SER A  17
ASP A  66
ARG A  68
GLU A 111
 None
 0.90A 5btfA-2z1nA:
undetectable
5btfC-2z1nA:
undetectable
5btfD-2z1nA:
1.9		 5btfA-2z1nA:
22.76
5btfC-2z1nA:
22.76
5btfD-2z1nA:
23.49