SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 2z2e LYSOZYME C, MILK
ISOZYME
(Canis
lupus) 		6 / 7 GLU A  35
ASP A  53
GLN A  58
ASN A  60
TRP A  64
TRP A 108
 None
 0.45A 4ii8A-2z2eA:
23.0		 4ii8A-2z2eA:
50.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 2z2e LYSOZYME C, MILK
ISOZYME
(Canis
lupus) 		4 / 8 ASP A  91
ALA A  95
VAL A  98
GLU A  35
 None
 0.87A 4zbqA-2z2eA:
undetectable		 4zbqA-2z2eA:
10.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 2z2e LYSOZYME C, MILK
ISOZYME
(Canis
lupus) 		5 / 5 GLU A  35
ASP A  53
TRP A 108
VAL A 109
ALA A 110
 None
 0.70A 5dl9A-2z2eA:
22.8		 5dl9A-2z2eA:
50.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 2z2e LYSOZYME C, MILK
ISOZYME
(Canis
lupus) 		5 / 12 ALA A 110
LEU A 120
SER A  24
LEU A  59
ILE A  92
 None
 1.23A 5hv1A-2z2eA:
undetectable		 5hv1A-2z2eA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2z2e LYSOZYME C, MILK
ISOZYME
(Canis
lupus) 		5 / 8 SER A  36
THR A  40
GLY A  55
ALA A  42
GLU A  35
 None
 1.19A 5vw9A-2z2eA:
undetectable		 5vw9A-2z2eA:
16.77