SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2z2f LYSOZYME C-2
(Bos
taurus) 		4 / 7 LEU A  25
LEU A   8
LEU A  15
GLY A  16
 None
 0.86A 1n13D-2z2fA:
undetectable
1n13E-2z2fA:
undetectable		 1n13D-2z2fA:
20.44
1n13E-2z2fA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2z2f LYSOZYME C-2
(Bos
taurus) 		4 / 6 ASP A  67
GLY A  68
THR A  70
PRO A  71
 None
 0.83A 1n4fA-2z2fA:
25.8		 1n4fA-2z2fA:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 2z2f LYSOZYME C-2
(Bos
taurus) 		5 / 11 ASP A  88
GLY A  55
SER A  36
PHE A  57
PHE A   3
 None
 1.26A 1w76A-2z2fA:
undetectable		 1w76A-2z2fA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W4X_A_STZA1591_1
(O-GLCNACASE BT_4395)		 2z2f LYSOZYME C-2
(Bos
taurus) 		5 / 11 ASP A 117
VAL A 120
TRP A 111
ASN A  27
VAL A  23
 None
 1.36A 2w4xA-2z2fA:
undetectable		 2w4xA-2z2fA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 2z2f LYSOZYME C-2
(Bos
taurus) 		5 / 12 ASP A 117
VAL A 120
TRP A 111
ASN A  27
VAL A  23
 None
 1.28A 2x0yA-2z2fA:
undetectable		 2x0yA-2z2fA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 2z2f LYSOZYME C-2
(Bos
taurus) 		4 / 7 TYR A  38
LEU A  29
LYS A  33
SER A 122
 None
 1.03A 3lslA-2z2fA:
undetectable
3lslD-2z2fA:
undetectable		 3lslA-2z2fA:
18.78
3lslD-2z2fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 2z2f LYSOZYME C-2
(Bos
taurus) 		4 / 7 SER A 122
TYR A  38
LEU A  29
LYS A  33
 None
 1.11A 3lslA-2z2fA:
undetectable
3lslD-2z2fA:
undetectable		 3lslA-2z2fA:
18.78
3lslD-2z2fA:
18.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 2z2f LYSOZYME C-2
(Bos
taurus) 		7 / 7 GLU A  35
ASP A  53
GLN A  58
ASN A  60
TRP A  64
ILE A  99
TRP A 108
 None
 0.28A 4ii8A-2z2fA:
25.7		 4ii8A-2z2fA:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2z2f LYSOZYME C-2
(Bos
taurus) 		4 / 7 THR A  11
LEU A  12
LEU A   8
THR A  40
 None
 0.92A 4z90A-2z2fA:
undetectable
4z90B-2z2fA:
undetectable
4z90C-2z2fA:
undetectable
4z90D-2z2fA:
undetectable
4z90E-2z2fA:
undetectable		 4z90A-2z2fA:
15.53
4z90B-2z2fA:
15.53
4z90C-2z2fA:
15.53
4z90D-2z2fA:
15.53
4z90E-2z2fA:
15.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 2z2f LYSOZYME C-2
(Bos
taurus) 		5 / 5 GLU A  35
ASP A  53
TRP A 108
VAL A 109
ALA A 110
 None
 0.32A 5dl9A-2z2fA:
25.6		 5dl9A-2z2fA:
54.62