SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 10 GLY A 218
PHE A 197
SER A 222
MET A 219
LEU A 223
 None
 1.45A 1a8uA-2z2mA:
undetectable		 1a8uA-2z2mA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		7 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
LYS B 547
SER B 548
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 2.9A)
CDS  B 901 ( 3.4A)
 0.41A 1ghmA-2z2mB:
16.2		 1ghmA-2z2mB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 ILE A  87
LEU A 200
ASP B 313
GLY A 191
PHE A 193
 None
 1.01A 1hvyD-2z2mA:
undetectable		 1hvyD-2z2mA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		7 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.41A 1i2wA-2z2mB:
16.2		 1i2wA-2z2mB:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
THR B 526
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
 0.46A 1i2wB-2z2mB:
16.2		 1i2wB-2z2mB:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.88A 1ictB-2z2mB:
undetectable		 1ictB-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 ALA B 508
LEU B 510
ILE B 348
SER B 504
 None
 1.06A 1sbrA-2z2mB:
undetectable
1sbrB-2z2mB:
undetectable		 1sbrA-2z2mB:
21.71
1sbrB-2z2mB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		7 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.54A 1ymxA-2z2mB:
16.6		 1ymxA-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.44A 1ymxB-2z2mB:
16.7		 1ymxB-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 GLY A 199
PHE B 427
THR B 430
SER A 217
 None
 1.05A 2a8tB-2z2mA:
undetectable		 2a8tB-2z2mA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 ASP B 582
LYS B 297
GLY B 299
THR B 304
 None
 1.05A 2aouA-2z2mB:
undetectable		 2aouA-2z2mB:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 ARG A  76
GLU A  89
ASN A 190
PRO A  86
 None
 1.41A 2ejfB-2z2mA:
undetectable		 2ejfB-2z2mA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae;
Streptococcus
pneumoniae) 		3 / 3 SER A 196
THR B 588
GLN B 458
 None
 0.58A 2fk8A-2z2mA:
undetectable		 2fk8A-2z2mA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_2
(MINERALOCORTICOID
RECEPTOR)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 4 LEU B 344
LEU B 517
MET B 400
MET B 386
 None
 1.45A 2oaxB-2z2mB:
0.0		 2oaxB-2z2mB:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.90A 2roxB-2z2mB:
undetectable		 2roxB-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 ILE A  87
ASP B 313
GLY A 191
PHE A 193
 None
 0.92A 2tsrB-2z2mA:
undetectable		 2tsrB-2z2mA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 PHE B 583
SER B 576
THR B 538
ASN B 605
ALA B 611
 None
 1.27A 2x2iC-2z2mB:
undetectable		 2x2iC-2z2mB:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 THR B 338
ILE B 569
GLY B 549
ALA B 551
VAL B 587
 None
None
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.7A)
None
 1.09A 2yvlD-2z2mB:
undetectable		 2yvlD-2z2mB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 ASN B 501
ALA B 508
ALA B 507
ALA B 345
 None
 0.85A 3a2qA-2z2mB:
undetectable		 3a2qA-2z2mB:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.86A 3cfqA-2z2mB:
undetectable
3cfqB-2z2mB:
undetectable		 3cfqA-2z2mB:
15.69
3cfqB-2z2mB:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.83A 3d2tA-2z2mB:
undetectable		 3d2tA-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		3 / 3 GLY B 422
PRO B 438
LEU B 416
 None
 0.56A 3hcpB-2z2mB:
undetectable		 3hcpB-2z2mB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 LYS B 340
SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.44A 3hlwA-2z2mB:
16.7		 3hlwA-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.28A 3hlwB-2z2mB:
16.8		 3hlwB-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.49A 3ny4A-2z2mB:
16.2		 3ny4A-2z2mB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 LYS B 340
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.32A 3q07A-2z2mB:
16.6		 3q07A-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 LYS B 340
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.58A 3q07B-2z2mB:
16.6		 3q07B-2z2mB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae;
Streptococcus
pneumoniae) 		3 / 3 THR A 159
ASP B 313
GLU A  89
 None
 0.70A 3qowA-2z2mA:
undetectable		 3qowA-2z2mA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
LYS B 340
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.30A 3sh8B-2z2mB:
16.8		 3sh8B-2z2mB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		3 / 3 GLY B 399
THR B 401
ASN B 397
 None
None
CDS  B 901 ( 3.0A)
 0.70A 3v4tD-2z2mB:
undetectable		 3v4tD-2z2mB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.76A 4d7bA-2z2mB:
undetectable		 4d7bA-2z2mB:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		7 / 12 LYS B 340
SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.64A 4euzA-2z2mB:
16.6		 4euzA-2z2mB:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 ASP A 208
ASN A 206
GLU A 205
ASP A 231
 None
 1.18A 4fewB-2z2mA:
undetectable		 4fewB-2z2mA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 11 ILE A  87
LEU A 200
ASP B 313
GLY A 191
PHE A 193
 None
 1.26A 4foxF-2z2mA:
undetectable		 4foxF-2z2mA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 ASP A 208
ASN A 206
GLU A 205
ASP A 231
 None
 1.15A 4gkhD-2z2mA:
undetectable		 4gkhD-2z2mA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.79A 4i89A-2z2mB:
undetectable		 4i89A-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.91A 4ikkA-2z2mB:
undetectable
4ikkB-2z2mB:
undetectable		 4ikkA-2z2mB:
17.07
4ikkB-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 5 GLY B 549
SER B 548
ALA B 572
PHE B 570
 CDS  B 901 ( 3.4A)
CDS  B 901 ( 2.9A)
None
None
 0.96A 4m93B-2z2mB:
undetectable
4m93C-2z2mB:
undetectable		 4m93B-2z2mB:
23.65
4m93C-2z2mB:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 LYS B 340
SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 4.2A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.70A 4pm7A-2z2mB:
16.9		 4pm7A-2z2mB:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 VAL B 539
ASN B 605
LEU B 600
VAL B 544
LEU B 546
 None
 1.38A 4po0A-2z2mB:
undetectable		 4po0A-2z2mB:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 THR B 526
THR B 550
ALA B 551
THR B 338
 CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.6A)
CDS  B 901 ( 3.7A)
None
 0.99A 4qw0K-2z2mB:
undetectable		 4qw0K-2z2mB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 THR B 526
THR B 550
ALA B 551
THR B 338
 CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.6A)
CDS  B 901 ( 3.7A)
None
 0.99A 4qw0Y-2z2mB:
undetectable		 4qw0Y-2z2mB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.79A 5bojA-2z2mB:
undetectable		 5bojA-2z2mB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae;
Streptococcus
pneumoniae) 		3 / 3 THR A 159
ASP B 313
GLU A  89
 None
 0.71A 5fa8A-2z2mA:
undetectable		 5fa8A-2z2mA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 337
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.26A 5ghyA-2z2mB:
16.6		 5ghyA-2z2mB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 337
SER B 395
ASN B 397
LYS B 547
GLY B 549
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.23A 5ghyB-2z2mB:
16.5		 5ghyB-2z2mB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 GLY B 500
VAL B 503
ALA B 508
ILE B 348
THR B 511
ALA B 469
 None
 1.47A 5hesA-2z2mB:
undetectable		 5hesA-2z2mB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 GLY B 500
VAL B 503
ALA B 508
ILE B 348
THR B 511
ALA B 469
 None
 1.47A 5hesB-2z2mB:
undetectable		 5hesB-2z2mB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 6 LEU B 585
ALA B 291
LEU B 293
THR B 305
 None
 0.78A 5l4iA-2z2mB:
undetectable		 5l4iA-2z2mB:
17.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ARG B 372
ASN B 377
ASN B 397
SER B 548
GLY B 549
GLN B 552
 None
None
CDS  B 901 ( 3.0A)
CDS  B 901 ( 2.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 4.2A)
 1.34A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ARG B 372
ASN B 377
ASN B 397
THR B 526
GLY B 549
GLN B 552
 None
None
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 4.2A)
 1.29A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 ARG B 372
ASN B 377
SER B 395
THR B 526
GLY B 549
 None
None
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
 1.08A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ARG B 372
ASN B 397
SER B 548
GLY B 549
THR B 550
GLN B 552
 None
CDS  B 901 ( 3.0A)
CDS  B 901 ( 2.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
CDS  B 901 ( 4.2A)
 1.39A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ARG B 372
ASN B 397
THR B 526
GLY B 549
THR B 550
GLN B 552
 None
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
CDS  B 901 ( 4.2A)
 1.33A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 ARG B 372
SER B 395
THR B 526
GLY B 549
THR B 550
 None
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 1.25A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ASN B 377
ASN B 397
GLN B 447
SER B 548
GLY B 549
GLN B 552
 None
CDS  B 901 ( 3.0A)
None
CDS  B 901 ( 2.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 4.2A)
 1.34A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 ASN B 377
ASN B 397
GLN B 447
THR B 526
GLY B 549
GLN B 552
 None
CDS  B 901 ( 3.0A)
None
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 4.2A)
 1.16A 5oj0A-2z2mB:
49.5		 5oj0A-2z2mB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 7 VAL A 114
ILE A 178
VAL A 149
ALA A  98
 None
 0.74A 5ospA-2z2mA:
undetectable		 5ospA-2z2mA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 MET B 527
ALA B 545
SER B 574
VAL B 341
PHE B 465
 None
 1.46A 5vlmH-2z2mB:
undetectable		 5vlmH-2z2mB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 ILE A  87
ASP B 313
GLY A 191
PHE A 193
 None
 0.88A 5x5qD-2z2mA:
undetectable		 5x5qD-2z2mA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		4 / 8 ILE A  87
ASP B 313
GLY A 191
PHE A 193
 None
 0.87A 5x5qF-2z2mA:
undetectable		 5x5qF-2z2mA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 9 THR B 459
ILE B 301
TYR B 586
THR B 588
THR B 290
 None
 1.44A 6b5yA-2z2mB:
16.0
6b5yB-2z2mB:
16.2		 6b5yA-2z2mB:
13.87
6b5yB-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.46A 6b5yB-2z2mB:
16.1		 6b5yB-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.52A 6b5yD-2z2mB:
15.9		 6b5yD-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 9 THR B 459
ILE B 301
TYR B 586
THR B 588
THR B 290
 None
 1.45A 6b68A-2z2mB:
16.1
6b68B-2z2mB:
16.2		 6b68A-2z2mB:
13.87
6b68B-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.34A 6b68B-2z2mB:
16.2		 6b68B-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.40A 6b68D-2z2mB:
16.1		 6b68D-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.35A 6b69A-2z2mB:
16.2
6b69B-2z2mB:
16.2		 6b69A-2z2mB:
13.87
6b69B-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.35A 6b69D-2z2mB:
16.0		 6b69D-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 9 THR B 459
ILE B 301
TYR B 586
THR B 588
THR B 290
 None
 1.46A 6b6aA-2z2mB:
16.0
6b6aB-2z2mB:
16.2		 6b6aA-2z2mB:
13.87
6b6aB-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.37A 6b6aB-2z2mB:
16.2		 6b6aB-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 9 THR B 459
ILE B 301
TYR B 586
THR B 588
THR B 290
 None
 1.49A 6b6aC-2z2mB:
16.0
6b6aD-2z2mB:
16.1		 6b6aC-2z2mB:
13.87
6b6aD-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 337
SER B 395
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.30A 6b6aD-2z2mB:
16.0		 6b6aD-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.61A 6b6dA-2z2mB:
15.9		 6b6dA-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		6 / 12 SER B 337
SER B 395
THR B 526
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.39A 6b6eA-2z2mB:
16.0		 6b6eA-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 337
SER B 395
LYS B 547
GLY B 549
THR B 550
 CDS  B 901 ( 1.3A)
CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
CDS  B 901 ( 3.6A)
 0.59A 6b6fA-2z2mB:
15.9		 6b6fA-2z2mB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 2z2m PENICILLIN-BINDING
PROTEIN 2X
(Streptococcus
pneumoniae) 		5 / 12 SER B 395
ASN B 397
THR B 526
LYS B 547
GLY B 549
 CDS  B 901 ( 3.2A)
CDS  B 901 ( 3.0A)
CDS  B 901 ( 4.1A)
CDS  B 901 ( 3.9A)
CDS  B 901 ( 3.4A)
 0.23A 6c79A-2z2mB:
16.6		 6c79A-2z2mB:
11.75