SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.99A 1v55P-2z2sA:
undetectable
1v55W-2z2sA:
undetectable		 1v55P-2z2sA:
18.66
1v55W-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 1.01A 2dysC-2z2sA:
undetectable
2dysJ-2z2sA:
undetectable		 2dysC-2z2sA:
18.66
2dysJ-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 1.02A 2eijP-2z2sA:
undetectable
2eijW-2z2sA:
undetectable		 2eijP-2z2sA:
18.66
2eijW-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.98A 2eilP-2z2sA:
undetectable
2eilW-2z2sA:
undetectable		 2eilP-2z2sA:
18.66
2eilW-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		3 / 3 ASP A  95
ARG A  93
ARG A  88
 None
 1.05A 2j9dA-2z2sA:
undetectable
2j9dC-2z2sA:
undetectable		 2j9dA-2z2sA:
23.91
2j9dC-2z2sA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 6 ILE A 130
LYS A  36
PHE A  40
PHE A 146
 None
 1.33A 3elzB-2z2sA:
undetectable		 3elzB-2z2sA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ASP A 102
PRO A 100
GLU A  99
ARG A  73
 None
 1.04A 3s3oA-2z2sA:
undetectable		 3s3oA-2z2sA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.92A 3x2qC-2z2sA:
undetectable
3x2qJ-2z2sA:
undetectable		 3x2qC-2z2sA:
18.66
3x2qJ-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.90A 5b1aC-2z2sA:
undetectable
5b1aJ-2z2sA:
undetectable		 5b1aC-2z2sA:
18.66
5b1aJ-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.86A 5b1aP-2z2sA:
undetectable
5b1aW-2z2sA:
undetectable		 5b1aP-2z2sA:
18.66
5b1aW-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.85A 5b3sC-2z2sA:
undetectable
5b3sJ-2z2sA:
undetectable		 5b3sC-2z2sA:
18.66
5b3sJ-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.85A 5b3sP-2z2sA:
undetectable		 5b3sP-2z2sA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		5 / 9 ILE A 165
LEU A 162
ARG A 132
ILE A 130
GLY A 127
 None
 1.43A 5ifuB-2z2sA:
undetectable		 5ifuB-2z2sA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.86A 5iy5C-2z2sA:
undetectable
5iy5J-2z2sA:
undetectable		 5iy5C-2z2sA:
19.17
5iy5J-2z2sA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.86A 5z84C-2z2sA:
undetectable
5z84J-2z2sA:
undetectable		 5z84C-2z2sA:
18.66
5z84J-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.85A 5z85C-2z2sA:
undetectable
5z85J-2z2sA:
undetectable		 5z85C-2z2sA:
18.66
5z85J-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.90A 5zcqC-2z2sA:
undetectable
5zcqJ-2z2sA:
undetectable		 5zcqC-2z2sA:
18.66
5zcqJ-2z2sA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z2s RPOE, ECF SIGE
(Rhodobacter
sphaeroides) 		4 / 7 ARG A  73
LEU A 176
GLN A 178
LEU A 103
 None
 0.86A 5zcqP-2z2sA:
undetectable
5zcqW-2z2sA:
undetectable		 5zcqP-2z2sA:
18.66
5zcqW-2z2sA:
17.88