SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 2z37 CHITINASE
(Brassica
juncea) 		4 / 7 SER A 266
TYR A 269
ASN A 268
TYR A 271
 None
 1.05A 1dssG-2z37A:
undetectable		 1dssG-2z37A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ILE A 340
ILE A 344
GLU A 201
ILE A 150
THR A 209
 None
 1.22A 1jtxA-2z37A:
undetectable		 1jtxA-2z37A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 PHE A 297
TYR A 157
TYR A 176
 None
 0.94A 1x70B-2z37A:
undetectable		 1x70B-2z37A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 2z37 CHITINASE
(Brassica
juncea) 		4 / 8 ALA A 178
PHE A 179
ALA A 183
LEU A 147
 None
 0.94A 2bxmA-2z37A:
undetectable		 2bxmA-2z37A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 ALA A 300
THR A 209
PHE A 186
 None
 0.60A 2c6nB-2z37A:
undetectable		 2c6nB-2z37A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 PHE A 205
GLY A 259
GLY A 275
LEU A 282
LEU A 280
 None
 1.05A 2hw2A-2z37A:
undetectable		 2hw2A-2z37A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 2z37 CHITINASE
(Brassica
juncea) 		4 / 6 HIS A 211
PHE A 364
TYR A 231
GLY A 216
 None
 1.09A 2i30A-2z37A:
undetectable		 2i30A-2z37A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 PHE A 206
PHE A 156
LEU A 160
ALA A 296
PHE A 297
 None
 1.25A 3apwB-2z37A:
undetectable		 3apwB-2z37A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 337
ILE A 343
ILE A 344
GLY A 207
PHE A 206
 None
 1.02A 3em0B-2z37A:
undetectable		 3em0B-2z37A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ALA A 289
GLY A 261
SER A 266
MET A 264
LEU A 282
 None
 1.04A 3ou6A-2z37A:
undetectable		 3ou6A-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.08A 3ou6A-2z37A:
undetectable		 3ou6A-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ALA A 289
GLY A 261
SER A 266
MET A 264
LEU A 282
 None
 1.07A 3ou6B-2z37A:
undetectable		 3ou6B-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.11A 3ou6B-2z37A:
undetectable		 3ou6B-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.11A 3ou6C-2z37A:
undetectable		 3ou6C-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.09A 3ou6D-2z37A:
undetectable		 3ou6D-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ALA A 289
GLY A 261
SER A 266
MET A 264
LEU A 282
 None
 1.07A 3ou7A-2z37A:
undetectable		 3ou7A-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.11A 3ou7A-2z37A:
undetectable		 3ou7A-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ALA A 289
GLY A 261
SER A 266
MET A 264
LEU A 282
 None
 1.07A 3ou7B-2z37A:
undetectable		 3ou7B-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.12A 3ou7C-2z37A:
undetectable		 3ou7C-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 ALA A 289
GLY A 261
SER A 266
MET A 264
LEU A 282
 None
 1.08A 3ou7D-2z37A:
undetectable		 3ou7D-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2z37 CHITINASE
(Brassica
juncea) 		5 / 12 TYR A 258
ALA A 289
SER A 266
MET A 264
LEU A 282
 None
 1.12A 3ou7D-2z37A:
undetectable		 3ou7D-2z37A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 LYS A 199
SER A 152
GLN A 155
 None
 1.24A 3si7A-2z37A:
undetectable		 3si7A-2z37A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 ARG A 353
PRO A 387
ASN A 389
 None
 1.03A 5jwaA-2z37A:
undetectable
5jwaH-2z37A:
undetectable		 5jwaA-2z37A:
18.58
5jwaH-2z37A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 PHE A 156
ASP A 154
LEU A 195
 None
 0.73A 5uhbC-2z37A:
undetectable		 5uhbC-2z37A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2z37 CHITINASE
(Brassica
juncea) 		3 / 3 PHE A 156
ASP A 154
LEU A 195
 None
 0.64A 5uhcC-2z37A:
undetectable		 5uhcC-2z37A:
12.32