SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A7Y_B_DVAB2_0 (ACTINOMYCIN D)	2z3q	INTERLEUKIN-15 RECEPTOR ALPHA CHAIN (Homo sapiens)	3 / 3	THR B 57 PRO B 59 THR B 58	None	0.84A	1a7yB-2z3qB: undetectable	1a7yB-2z3qB: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MNV_D_DVAD2_0 (ACTINOMYCIN D)	2z3q	INTERLEUKIN-15 RECEPTOR ALPHA CHAIN (Homo sapiens)	3 / 3	THR B 57 PRO B 59 THR B 58	None	0.85A	1mnvD-2z3qB: undetectable	1mnvD-2z3qB: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_F_DVAF2_0 (7-AMINO-ACTINOMYCIN D)	2z3q	INTERLEUKIN-15 RECEPTOR ALPHA CHAIN (Homo sapiens)	3 / 3	THR B 57 PRO B 59 THR B 58	None	0.83A	1unjF-2z3qB: undetectable	1unjF-2z3qB: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_F_DVAF8_0 (7-AMINO-ACTINOMYCIN D)	2z3q	INTERLEUKIN-15 RECEPTOR ALPHA CHAIN (Homo sapiens)	3 / 3	THR B 58 THR B 57 PRO B 59	None	0.84A	1unjF-2z3qB: undetectable	1unjF-2z3qB: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_R_DVAR2_0 (7-AMINO-ACTINOMYCIN D)	2z3q	INTERLEUKIN-15 RECEPTOR ALPHA CHAIN (Homo sapiens)	3 / 3	THR B 57 PRO B 59 THR B 58	None	0.86A	1unjR-2z3qB: undetectable	1unjR-2z3qB: 9.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A7Y_B_DVAB2_0","ACTINOMYCIN D","2z3q","INTERLEUKIN-15 RECEPTOR ALPHA CHAIN","Homo sapiens",3,"THR B  57;PRO B  59;THR B  58","None","0.84A","1a7yB-2z3qB:undetectable","1a7yB-2z3qB:9.52"],["1MNV_D_DVAD2_0","ACTINOMYCIN D","2z3q","INTERLEUKIN-15 RECEPTOR ALPHA CHAIN","Homo sapiens",3,"THR B  57;PRO B  59;THR B  58","None","0.85A","1mnvD-2z3qB:undetectable","1mnvD-2z3qB:9.52"],["1UNJ_F_DVAF2_0","7-AMINO-ACTINOMYCIN D","2z3q","INTERLEUKIN-15 RECEPTOR ALPHA CHAIN","Homo sapiens",3,"THR B  57;PRO B  59;THR B  58","None","0.83A","1unjF-2z3qB:undetectable","1unjF-2z3qB:9.52"],["1UNJ_F_DVAF8_0","7-AMINO-ACTINOMYCIN D","2z3q","INTERLEUKIN-15 RECEPTOR ALPHA CHAIN","Homo sapiens",3,"THR B  58;THR B  57;PRO B  59","None","0.84A","1unjF-2z3qB:undetectable","1unjF-2z3qB:9.52"],["1UNJ_R_DVAR2_0","7-AMINO-ACTINOMYCIN D","2z3q","INTERLEUKIN-15 RECEPTOR ALPHA CHAIN","Homo sapiens",3,"THR B  57;PRO B  59;THR B  58","None","0.86A","1unjR-2z3qB:undetectable","1unjR-2z3qB:9.52"]]