SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2z4r CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Thermotoga
maritima) 		4 / 8 ALA A 325
LEU A 328
LEU A 309
LYS A 313
 None
 0.86A 4po0A-2z4rA:
2.0		 4po0A-2z4rA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2z4r CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Thermotoga
maritima) 		4 / 9 ALA A 120
LEU A 147
LEU A 199
ILE A 230
 None
 0.97A 4xtaA-2z4rA:
undetectable		 4xtaA-2z4rA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 2z4r CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Thermotoga
maritima) 		4 / 6 GLY A 110
PRO A 111
THR A 267
GLU A 266
 None
 0.94A 5ny7A-2z4rA:
undetectable		 5ny7A-2z4rA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2z4r CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Thermotoga
maritima) 		4 / 8 PHE A 134
SER A 168
PHE A 252
LEU A 241
 None
 1.08A 5y2tB-2z4rA:
undetectable		 5y2tB-2z4rA:
undetectable