SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		4 / 6 ILE A  59
ARG A  62
LEU A  63
LEU A  20
 None
 0.93A 2rlfA-2z51A:
undetectable
2rlfD-2z51A:
undetectable		 2rlfA-2z51A:
14.39
2rlfD-2z51A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		5 / 11 VAL A  27
GLY A  25
PRO A  49
SER A  50
THR A  52
 None
 1.18A 3bjwB-2z51A:
undetectable		 3bjwB-2z51A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		5 / 11 VAL A  27
GLY A  25
PRO A  49
SER A  50
THR A  52
 None
 1.15A 3bjwE-2z51A:
undetectable		 3bjwE-2z51A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		4 / 5 VAL A  36
VAL A  37
ARG A  38
LYS A  56
 None
 1.41A 3rv5A-2z51A:
undetectable
3rv5B-2z51A:
undetectable		 3rv5A-2z51A:
23.81
3rv5B-2z51A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		5 / 12 VAL A  27
ILE A  59
GLU A   7
HIS A  30
VAL A  73
 None
 1.01A 4a97B-2z51A:
undetectable
4a97C-2z51A:
undetectable		 4a97B-2z51A:
17.59
4a97C-2z51A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		4 / 5 VAL A  39
LEU A  29
LEU A  13
ILE A  70
 None
 0.95A 4a9jB-2z51A:
undetectable		 4a9jB-2z51A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		4 / 5 VAL A  39
LEU A  29
LEU A  13
ILE A  70
 None
 0.94A 4a9jC-2z51A:
undetectable		 4a9jC-2z51A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		4 / 8 VAL A  39
LEU A  29
LEU A  13
ILE A  70
 None
 0.89A 4lzrA-2z51A:
undetectable		 4lzrA-2z51A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		5 / 11 GLY A 103
ALA A 105
ILE A 123
THR A 124
GLY A 125
 None
 0.84A 4qgiA-2z51A:
undetectable		 4qgiA-2z51A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST
(Arabidopsis
thaliana) 		5 / 12 GLN A  42
ALA A  28
LEU A  20
ILE A  16
VAL A   9
 None
 1.22A 5vlmB-2z51A:
2.4		 5vlmB-2z51A:
25.50