SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z5b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2z5b UNCHARACTERIZED
PROTEIN YLR021W
(Saccharomyces
cerevisiae) 		4 / 4 ILE B 143
LEU B  27
VAL B 169
ILE B 173
 None
 0.71A 1fm6D-2z5bB:
undetectable		 1fm6D-2z5bB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2z5b UNCHARACTERIZED
PROTEIN YLR021W
(Saccharomyces
cerevisiae) 		4 / 8 GLU B  26
GLN B   7
VAL B 169
CYH B 172
 None
 1.26A 3b9lA-2z5bB:
undetectable		 3b9lA-2z5bB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 2z5b UNCHARACTERIZED
PROTEIN YLR021W
(Saccharomyces
cerevisiae) 		3 / 3 PHE B 168
CYH B 172
PHE B   6
 None
 1.07A 3cr5X-2z5bB:
undetectable		 3cr5X-2z5bB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2z5b UNCHARACTERIZED
PROTEIN YLR021W
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 116
ALA B 117
LEU B 141
ILE B 149
LEU B 166
 None
 0.97A 3oapA-2z5bB:
undetectable		 3oapA-2z5bB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2z5b UNCHARACTERIZED
PROTEIN YLR021W
(Saccharomyces
cerevisiae) 		4 / 7 GLU B  47
ASP B  49
TRP B 150
ILE B 149
 None
 1.16A 4ii8A-2z5bB:
undetectable		 4ii8A-2z5bB:
20.44