SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETB_2_T442129_1 (TRANSTHYRETIN)	2z5e	PROTEASOME ASSEMBLING CHAPERONE 3 (Homo sapiens)	4 / 6	LYS A 65 LEU A 67 THR A 63 LEU A 45	None	1.07A	1etb2-2z5eA: undetectable	1etb2-2z5eA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M56_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	2z5e	PROTEASOME ASSEMBLING CHAPERONE 3 (Homo sapiens)	4 / 5	PHE A 85 LEU A 97 VAL A 34 VAL A 115	None	1.22A	2m56A-2z5eA: undetectable	2m56A-2z5eA: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9L_A_AZZA1009_1 (SERUM ALBUMIN)	2z5e	PROTEASOME ASSEMBLING CHAPERONE 3 (Homo sapiens)	4 / 8	GLU A 89 GLN A 120 VAL A 23 CYH A 25	None	1.11A	3b9lA-2z5eA: undetectable	3b9lA-2z5eA: 11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G3R_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	2z5e	PROTEASOME ASSEMBLING CHAPERONE 3 (Homo sapiens)	4 / 6	PHE A 85 LEU A 97 VAL A 34 VAL A 115	None	1.14A	4g3rB-2z5eA: undetectable	4g3rB-2z5eA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Y_D_9CRD501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2z5e	PROTEASOME ASSEMBLING CHAPERONE 3 (Homo sapiens)	3 / 3	ASN A 81 VAL A 66 HIS A 76	None	0.70A	6a5yD-2z5eA: undetectable	6a5yD-2z5eA: 23.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ETB_2_T442129_1","TRANSTHYRETIN","2z5e","PROTEASOME ASSEMBLING CHAPERONE 3","Homo sapiens",4,"LYS A  65;LEU A  67;THR A  63;LEU A  45","None","1.07A","1etb2-2z5eA:undetectable","1etb2-2z5eA:22.92"],["2M56_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","2z5e","PROTEASOME ASSEMBLING CHAPERONE 3","Homo sapiens",4,"PHE A  85;LEU A  97;VAL A  34;VAL A 115","None","1.22A","2m56A-2z5eA:undetectable","2m56A-2z5eA:15.15"],["3B9L_A_AZZA1009_1","SERUM ALBUMIN","2z5e","PROTEASOME ASSEMBLING CHAPERONE 3","Homo sapiens",4,"GLU A  89;GLN A 120;VAL A  23;CYH A  25","None","1.11A","3b9lA-2z5eA:undetectable","3b9lA-2z5eA:11.79"],["4G3R_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","2z5e","PROTEASOME ASSEMBLING CHAPERONE 3","Homo sapiens",4,"PHE A  85;LEU A  97;VAL A  34;VAL A 115","None","1.14A","4g3rB-2z5eA:undetectable","4g3rB-2z5eA:15.02"],["6A5Y_D_9CRD501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2z5e","PROTEASOME ASSEMBLING CHAPERONE 3","Homo sapiens",3,"ASN A  81;VAL A  66;HIS A  76","None","0.70A","6a5yD-2z5eA:undetectable","6a5yD-2z5eA:23.68"]]