SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 117
TYR A 116
GLN A 119
 None
 0.65A 2wekA-2z69A:
undetectable		 2wekA-2z69A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 110
PHE A 109
PHE A   3
ILE A  57
 None
 0.84A 2zseA-2z69A:
undetectable		 2zseA-2z69A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		5 / 6 PHE A 111
PHE A  53
ASN A 113
ALA A 115
LEU A  20
 None
 1.32A 4ejgD-2z69A:
undetectable		 4ejgD-2z69A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  10
LEU A  11
LEU A  25
ILE A  57
GLN A 107
 None
 1.28A 4f4dA-2z69A:
undetectable		 4f4dA-2z69A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 VAL A  61
ILE A  63
VAL A  43
ALA A 100
 None
 0.73A 5ospA-2z69A:
undetectable		 5ospA-2z69A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 123
PRO A  19
GLN A  12
 None
 0.85A 6jnhA-2z69A:
undetectable		 6jnhA-2z69A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2z69 DNR PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 123
PRO A  19
GLN A  12
 None
 0.86A 6jogA-2z69A:
undetectable		 6jogA-2z69A:
18.71