SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		4 / 5 ARG D  41
MET D  40
THR D  39
LEU D  38
 None
 1.38A 2eimJ-2z6bD:
undetectable		 2eimJ-2z6bD:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		4 / 5 ARG D  41
MET D  40
THR D  39
LEU D  38
 None
 1.35A 2eimW-2z6bD:
undetectable		 2eimW-2z6bD:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		4 / 5 ASN D  78
ALA D  77
GLY D   8
TYR D   9
 None
 1.22A 3bcrA-2z6bD:
undetectable		 3bcrA-2z6bD:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		3 / 3 GLU D  49
GLY D 110
THR D 111
 None
 0.53A 3iazA-2z6bD:
undetectable		 3iazA-2z6bD:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		5 / 11 TYR D 172
TYR D 169
PHE D 166
TRP D 162
GLU D 175
 None
 1.45A 3m8pA-2z6bD:
undetectable
3m8pB-2z6bD:
undetectable		 3m8pA-2z6bD:
20.42
3m8pB-2z6bD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		4 / 7 GLU D 108
ARG D  41
THR D  39
GLY D  50
 None
 0.85A 4qwpB-2z6bD:
undetectable		 4qwpB-2z6bD:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		3 / 3 SER D 131
TYR D 169
ASP D 159
 None
 0.81A 4rp8C-2z6bD:
undetectable		 4rp8C-2z6bD:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		5 / 12 PHE D 234
CYH D 310
LEU D 318
PHE D 326
MET D 211
 None
 0.99A 4xldA-2z6bD:
undetectable		 4xldA-2z6bD:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		3 / 3 SER D 257
SER D 278
PHE D 376
 None
 0.77A 5mugA-2z6bD:
undetectable		 5mugA-2z6bD:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		5 / 10 PRO D 210
GLY D 314
THR D 353
ILE D 313
ALA D 231
 None
 1.12A 5vyhA-2z6bD:
undetectable		 5vyhA-2z6bD:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		5 / 12 PHE D 234
CYH D 310
LEU D 318
PHE D 326
MET D 211
 None
 1.03A 5y2oA-2z6bD:
undetectable		 5y2oA-2z6bD:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 2z6b BASEPLATE STRUCTURAL
PROTEIN GP27
(Escherichia
virus
T4) 		4 / 6 GLU D 294
ARG D 279
VAL D 157
PRO D 158
 None
 1.26A 6fgdA-2z6bD:
undetectable		 6fgdA-2z6bD:
21.74