SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z6k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		4 / 8 PHE A 135
MET A 102
ALA A  57
PHE A  64
 None
 0.79A 1epbB-2z6kA:
undetectable		 1epbB-2z6kA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		3 / 3 PHE A  64
LYS A 139
SER A 140
 None
 1.34A 3tyeB-2z6kA:
undetectable		 3tyeB-2z6kA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		5 / 10 GLY A  78
VAL A 126
GLU A 154
ASP A  96
ILE A  94
 None
 1.14A 5i3cB-2z6kA:
undetectable		 5i3cB-2z6kA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		4 / 7 HIS A 131
HIS A  45
ILE A  46
GLN A  44
 None
 1.30A 5kkzC-2z6kA:
undetectable
5kkzE-2z6kA:
undetectable		 5kkzC-2z6kA:
21.74
5kkzE-2z6kA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		4 / 7 HIS A  45
ILE A  46
GLN A  44
HIS A 131
 None
 1.28A 5kkzK-2z6kA:
undetectable
5kkzQ-2z6kA:
undetectable		 5kkzK-2z6kA:
19.64
5kkzQ-2z6kA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT
(Homo
sapiens) 		4 / 7 HIS A 131
HIS A  45
ILE A  46
GLN A  44
 None
 1.31A 5kkzM-2z6kA:
undetectable
5kkzO-2z6kA:
undetectable		 5kkzM-2z6kA:
21.74
5kkzO-2z6kA:
19.64