SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 TYR A 104
LEU A 106
SER A 114
HIS A 175
ILE A 102
 None
 1.18A 1fmlB-2z6vA:
10.0		 1fmlB-2z6vA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 TRP A 196
HIS A 235
MET A 203
 None
 1.27A 1l5qB-2z6vA:
0.5		 1l5qB-2z6vA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 TYR A 104
SER A 114
HIS A 175
HIS A 232
 None
 1.49A 1s19A-2z6vA:
0.0		 1s19A-2z6vA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 TRP A 196
MET A 172
ALA A 194
LEU A 197
 None
PLM  A 700 (-4.1A)
None
None
 1.02A 2o01A-2z6vA:
undetectable		 2o01A-2z6vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 ALA A 246
LEU A 239
ILE A 306
PHE A 311
 None
 0.82A 2w9sE-2z6vA:
undetectable		 2w9sE-2z6vA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 ARG A  53
PHE A 187
LEU A  57
PHE A   4
 None
 1.35A 2y69P-2z6vA:
undetectable
2y69W-2z6vA:
undetectable		 2y69P-2z6vA:
17.17
2y69W-2z6vA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 LEU A 338
GLN A 108
THR A 342
LEU A  89
 None
 1.09A 3ce6D-2z6vA:
undetectable		 3ce6D-2z6vA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 HIS A  77
ASP A  76
TYR A  73
PRO A 126
 None
 1.47A 3fo7A-2z6vA:
undetectable		 3fo7A-2z6vA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 CYH A 120
PRO A 168
ASP A 171
 None
 0.80A 3hlwB-2z6vA:
undetectable		 3hlwB-2z6vA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 GLN A 108
THR A 342
LEU A  89
 None
 0.76A 3ondA-2z6vA:
undetectable		 3ondA-2z6vA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 ARG A 345
GLU A 343
THR A 339
 None
 0.93A 3v4tA-2z6vA:
undetectable		 3v4tA-2z6vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 7 TYR A  73
HIS A  77
ILE A  74
PRO A 126
 None
 1.16A 4g5jA-2z6vA:
undetectable		 4g5jA-2z6vA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 LEU A 197
LEU A  35
TRP A 196
TYR A 193
ALA A 201
 None
 1.37A 4hwkB-2z6vA:
undetectable		 4hwkB-2z6vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 LEU A 197
LEU A  35
TRP A 196
TYR A 193
ALA A 201
 None
 1.38A 4hwkC-2z6vA:
2.2		 4hwkC-2z6vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 LEU A 197
LEU A  35
TRP A 196
TYR A 193
ALA A 201
 None
 1.34A 4hwkD-2z6vA:
1.6		 4hwkD-2z6vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 SER A 226
ARG A 112
LEU A 106
ASP A 107
 None
 1.44A 4ifxA-2z6vA:
undetectable		 4ifxA-2z6vA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 SER A 226
ARG A 112
LEU A 106
ASP A 107
 None
 1.40A 4ig1A-2z6vA:
undetectable		 4ig1A-2z6vA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 6 ARG A 212
ASP A 178
VAL A  13
ALA A  10
 None
 0.98A 4nkxA-2z6vA:
undetectable		 4nkxA-2z6vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 CYH A 120
PRO A 168
ASP A 171
 None
 0.76A 4pm5A-2z6vA:
undetectable		 4pm5A-2z6vA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 5 TYR A 368
GLY A 260
THR A 259
LEU A 268
 None
 0.93A 5jlcA-2z6vA:
undetectable		 5jlcA-2z6vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 LEU A 300
HIS A 252
ASP A 308
GLY A 307
HIS A 313
 None
 1.19A 5nnaA-2z6vA:
undetectable		 5nnaA-2z6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 LEU A 300
HIS A 252
ASP A 308
GLY A 307
HIS A 313
 None
 1.18A 5nnaB-2z6vA:
undetectable		 5nnaB-2z6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 LEU A 300
HIS A 252
ASP A 308
GLY A 307
HIS A 313
 None
 1.15A 5nnaC-2z6vA:
undetectable		 5nnaC-2z6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 6 SER A 233
HIS A 295
PHE A 198
GLN A 291
 None
PLM  A 700 (-3.8A)
None
PLM  A 700 (-3.1A)
 1.48A 5u6nB-2z6vA:
undetectable		 5u6nB-2z6vA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 ASP A  59
PHE A   4
ARG A  20
 None
 1.13A 5yw0A-2z6vA:
undetectable		 5yw0A-2z6vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 ASP A 254
ASP A 366
THR A 259
GLY A 260
GLU A 367
 None
 1.43A 6mb9B-2z6vA:
undetectable		 6mb9B-2z6vA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 ASP A 254
ASP A 366
THR A 259
GLY A 260
GLU A 367
 None
 1.41A 6mb9C-2z6vA:
undetectable		 6mb9C-2z6vA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 ARG A  53
PHE A 187
PHE A   4
 None
 0.85A 6nknC-2z6vA:
undetectable
6nknJ-2z6vA:
undetectable		 6nknC-2z6vA:
17.17
6nknJ-2z6vA:
10.86