SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.93A 1bx4A-2z84A:
undetectable		 1bx4A-2z84A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 1.05A 1liiA-2z84A:
undetectable		 1liiA-2z84A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		4 / 6 TRP A 179
LEU A  75
ARG A  49
GLY A  50
 None
 1.16A 2hs2B-2z84A:
undetectable		 2hs2B-2z84A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 LEU A 127
GLY A 129
VAL A 202
GLY A 160
ARG A 133
 None
 1.03A 2vmyA-2z84A:
undetectable		 2vmyA-2z84A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.92A 3uq6A-2z84A:
undetectable		 3uq6A-2z84A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.93A 3vaqA-2z84A:
undetectable		 3vaqA-2z84A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.94A 3vasA-2z84A:
undetectable		 3vasA-2z84A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.91A 3vasB-2z84A:
undetectable		 3vasB-2z84A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.92A 4dc3B-2z84A:
undetectable		 4dc3B-2z84A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		3 / 3 PHE A 203
VAL A 199
GLU A 131
 None
 0.75A 4fvqA-2z84A:
undetectable		 4fvqA-2z84A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		4 / 7 HIS A 177
PRO A 176
ASP A 175
SER A 201
 None
 1.19A 4odjA-2z84A:
undetectable		 4odjA-2z84A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 11 LEU A 121
LEU A 211
LEU A 127
GLU A 132
LEU A 134
 None
 1.15A 4wg0J-2z84A:
undetectable
4wg0K-2z84A:
undetectable
4wg0L-2z84A:
undetectable		 4wg0J-2z84A:
7.53
4wg0K-2z84A:
7.53
4wg0L-2z84A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 ASP A 152
LEU A 127
GLY A 149
GLY A 148
LEU A 121
 None
 0.97A 5kb5A-2z84A:
undetectable		 5kb5A-2z84A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 2z84 UFM1-SPECIFIC
PROTEASE 1
(Mus
musculus) 		5 / 12 LEU A  75
LEU A  78
ALA A  81
SER A 105
LEU A 108
 None
 1.17A 5mwyA-2z84A:
undetectable		 5mwyA-2z84A:
18.69