SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2z9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 PHE A  42
SER A  60
ALA A  58
ILE A  57
 None
 0.96A 1fxhA-2z9sA:
undetectable
1fxhB-2z9sA:
undetectable		 1fxhA-2z9sA:
19.65
1fxhB-2z9sA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 11 LEU A  85
LEU A 104
ALA A  58
VAL A  20
MET A 100
 None
 1.44A 1kt6A-2z9sA:
undetectable		 1kt6A-2z9sA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 11 LEU A  85
LEU A 104
ALA A  58
VAL A  20
MET A 100
 None
 1.41A 1kt7A-2z9sA:
undetectable		 1kt7A-2z9sA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 ASP A  61
PHE A  59
MET A 100
LEU A 104
 None
 1.07A 1lhvA-2z9sA:
undetectable		 1lhvA-2z9sA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 6 ASP A 107
PHE A  43
ASP A 115
TYR A 116
 None
 1.22A 2todA-2z9sA:
undetectable
2todB-2z9sA:
undetectable		 2todA-2z9sA:
18.12
2todB-2z9sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_B_DMOB700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 ASP A 115
TYR A 116
ASP A 107
PHE A  43
 None
 1.25A 2todA-2z9sA:
0.0
2todB-2z9sA:
0.0		 2todA-2z9sA:
18.12
2todB-2z9sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_C_DMOC700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 ASP A 107
PHE A  43
ASP A 115
TYR A 116
 None
 1.26A 2todC-2z9sA:
0.0
2todD-2z9sA:
0.0		 2todC-2z9sA:
18.12
2todD-2z9sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_D_DMOD700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 ASP A 115
TYR A 116
ASP A 107
PHE A  43
 None
 1.24A 2todC-2z9sA:
0.0
2todD-2z9sA:
0.0		 2todC-2z9sA:
18.12
2todD-2z9sA:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.32A 2v2gA-2z9sA:
22.6
2v2gB-2z9sA:
22.6		 2v2gA-2z9sA:
30.17
2v2gB-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.33A 2v2gA-2z9sA:
22.6
2v2gB-2z9sA:
22.6		 2v2gA-2z9sA:
30.17
2v2gB-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.32A 2v2gC-2z9sA:
22.5
2v2gD-2z9sA:
22.6		 2v2gC-2z9sA:
30.17
2v2gD-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.33A 2v2gC-2z9sA:
22.5
2v2gD-2z9sA:
22.6		 2v2gC-2z9sA:
30.17
2v2gD-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.38A 2v32A-2z9sA:
22.5
2v32B-2z9sA:
22.6		 2v32A-2z9sA:
30.17
2v32B-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.32A 2v32A-2z9sA:
22.5
2v32B-2z9sA:
22.6		 2v32A-2z9sA:
30.17
2v32B-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 8 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.33A 2v32C-2z9sA:
22.5
2v32D-2z9sA:
22.6		 2v32C-2z9sA:
30.17
2v32D-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.36A 2v32C-2z9sA:
22.5
2v32D-2z9sA:
22.6		 2v32C-2z9sA:
30.17
2v32D-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 9 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.28A 2v41A-2z9sA:
22.4
2v41B-2z9sA:
22.6		 2v41A-2z9sA:
30.17
2v41B-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 9 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.32A 2v41A-2z9sA:
22.4
2v41B-2z9sA:
22.6		 2v41A-2z9sA:
30.17
2v41B-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 8 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.34A 2v41C-2z9sA:
22.8
2v41D-2z9sA:
22.6		 2v41C-2z9sA:
30.17
2v41D-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 8 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.33A 2v41C-2z9sA:
22.8
2v41D-2z9sA:
22.6		 2v41C-2z9sA:
30.17
2v41D-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.30A 2v41E-2z9sA:
22.2
2v41F-2z9sA:
22.3		 2v41E-2z9sA:
30.17
2v41F-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.34A 2v41E-2z9sA:
22.2
2v41F-2z9sA:
22.3		 2v41E-2z9sA:
30.17
2v41F-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.33A 2v41G-2z9sA:
22.3
2v41H-2z9sA:
22.5		 2v41G-2z9sA:
30.17
2v41H-2z9sA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		5 / 8 PRO A  45
THR A  49
VAL A  51
SER A  52
ARG A 128
 None
 0.37A 2v41G-2z9sA:
22.3
2v41H-2z9sA:
22.4		 2v41G-2z9sA:
30.17
2v41H-2z9sA:
30.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 ALA A  19
LEU A 104
ALA A  76
PHE A  43
 None
 0.94A 2vcvL-2z9sA:
2.1		 2vcvL-2z9sA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 PRO A 103
ALA A  19
LEU A 104
ALA A  76
 None
 1.07A 2vcvL-2z9sA:
2.1		 2vcvL-2z9sA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		3 / 3 ARG A 128
GLU A  55
SER A   3
 None
 0.75A 2xctD-2z9sA:
undetectable		 2xctD-2z9sA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 ILE A  56
SER A  52
PRO A  53
PHE A  50
 None
 1.34A 3bjwC-2z9sA:
undetectable		 3bjwC-2z9sA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 LYS A  68
LEU A  69
GLU A  65
LEU A 157
 None
 1.17A 4k4yA-2z9sA:
undetectable		 4k4yA-2z9sA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 4 LYS A  68
LEU A  69
GLU A  65
LEU A 157
 None
 1.16A 4k4yE-2z9sA:
undetectable		 4k4yE-2z9sA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 5 LYS A  68
LEU A  69
GLU A  65
LEU A 157
 None
 1.18A 4k4yI-2z9sA:
undetectable		 4k4yI-2z9sA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 ASP A 167
TYR A  38
GLY A  36
ALA A  12
 None
 0.93A 4m48A-2z9sA:
undetectable		 4m48A-2z9sA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 ILE A   8
GLY A   9
PHE A 165
ASP A 134
 None
 0.82A 5hieB-2z9sA:
undetectable		 5hieB-2z9sA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 7 ILE A 125
GLY A 124
ASP A 107
PHE A  15
 None
 0.86A 5hieB-2z9sA:
undetectable		 5hieB-2z9sA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 ILE A   8
GLY A   9
PHE A 165
ASP A 134
 None
 0.82A 5hieD-2z9sA:
undetectable		 5hieD-2z9sA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2z9s PEROXIREDOXIN-1
(Rattus
norvegicus) 		4 / 8 ILE A 125
GLY A 124
ASP A 107
PHE A  15
 None
 0.88A 5hieD-2z9sA:
undetectable		 5hieD-2z9sA:
21.26