SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2za8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		5 / 12 LEU A 117
LEU A 114
LEU A 111
ALA A 110
LEU A  23
 None
 0.86A 1s9pC-2za8A:
undetectable		 1s9pC-2za8A:
23.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 4 LEU A  25
SER A  28
TYR A  29
LEU A  82
 None
 0.08A 1xz1A-2za8A:
28.7		 1xz1A-2za8A:
99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 4 LEU A  25
SER A  28
TYR A  29
LEU A  82
 None
 0.08A 1xz3A-2za8A:
28.7		 1xz3A-2za8A:
99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		6 / 6 LEU A  25
SER A  28
TYR A  29
LEU A  32
ARG A  60
LEU A  82
 None
 0.52A 3f33A-2za8A:
28.4		 3f33A-2za8A:
99.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		5 / 12 THR A  93
GLU A 164
LEU A 149
LEU A  34
TYR A  31
 None
 1.47A 3gwxB-2za8A:
undetectable		 3gwxB-2za8A:
21.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		6 / 6 LEU A  25
SER A  28
TYR A  29
ALA A  56
ARG A  60
LEU A  82
 None
 0.60A 3ravA-2za8A:
28.7		 3ravA-2za8A:
99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 6 LEU A  25
SER A  28
ARG A  60
LEU A  82
 None
 0.62A 3rd0A-2za8A:
28.8		 3rd0A-2za8A:
99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		5 / 6 LEU A  25
SER A  28
TYR A  29
ALA A  56
LEU A  82
 None
 0.13A 3rd0A-2za8A:
28.8		 3rd0A-2za8A:
99.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 6 TYR A  24
LYS A  59
LEU A 103
GLU A 104
 None
 0.89A 4f3tA-2za8A:
undetectable		 4f3tA-2za8A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 5 TYR A  24
LYS A  59
LEU A 103
GLU A 104
 None
 0.97A 4olaA-2za8A:
undetectable		 4olaA-2za8A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 6 TYR A  24
LYS A  59
LEU A 103
GLU A 104
 None
 0.93A 4z4cA-2za8A:
undetectable		 4z4cA-2za8A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 5 TYR A  24
LYS A  59
LEU A 103
GLU A 104
 None
 0.93A 4z4hA-2za8A:
undetectable		 4z4hA-2za8A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 5 TYR A  24
LYS A  59
LEU A 103
GLU A 104
 None
 0.80A 5js1A-2za8A:
undetectable		 5js1A-2za8A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 2za8 FERRITIN LIGHT CHAIN
(Equus
caballus) 		4 / 5 GLY A 118
LEU A 126
SER A  10
GLN A 121
 None
 1.23A 6ji6A-2za8A:
undetectable		 6ji6A-2za8A:
21.52