SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		5 / 12 TYR A 310
THR A 380
GLY A 140
ILE A 379
CYH A 267
 None
 1.05A 2akeA-2zahA:
undetectable		 2akeA-2zahA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		3 / 3 ASN A 132
ASN A 286
ARG A 126
 None
 0.94A 2rlcA-2zahA:
undetectable		 2rlcA-2zahA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		5 / 10 PHE A 326
SER A 330
SER A 353
VAL A 302
GLY A 301
 None
 1.43A 2x2iD-2zahA:
2.4		 2x2iD-2zahA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		3 / 3 ASN A 203
ASP A 196
ARG A 175
 None
 0.78A 3k13C-2zahA:
undetectable		 3k13C-2zahA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		4 / 6 TYR A 310
ILE A 379
SER A 330
SER A 353
 None
 1.09A 3pmzD-2zahA:
undetectable		 3pmzD-2zahA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		4 / 6 TYR A 310
MET A 377
ILE A 379
SER A 353
 None
 1.02A 3pmzD-2zahA:
undetectable		 3pmzD-2zahA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		4 / 6 GLU A 255
LYS A  97
LYS A 257
TRP A 213
 None
 1.42A 4a7tF-2zahA:
undetectable		 4a7tF-2zahA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		4 / 7 ILE A 288
PHE A 364
GLY A 301
LEU A 316
 None
 1.00A 5esmA-2zahA:
undetectable		 5esmA-2zahA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		4 / 6 PRO A 307
TYR A 252
LEU A 248
LEU A 134
 None
 1.16A 5tl8A-2zahA:
undetectable		 5tl8A-2zahA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2zah COAT PROTEIN
(Melon
necrotic
spot
virus) 		5 / 10 PHE A 232
GLY A 123
ILE A 306
ALA A 133
LEU A 134
 None
 1.17A 5zjiA-2zahA:
undetectable
5zjiJ-2zahA:
undetectable		 5zjiA-2zahA:
11.84
5zjiJ-2zahA:
8.61