SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC
(Sulfurisphaera
tokodaii) 		3 / 3 GLY A  14
GLU A  17
ASP A  11
 None
 0.68A 2b25B-2zbcA:
undetectable		 2b25B-2zbcA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC
(Sulfurisphaera
tokodaii) 		4 / 5 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.16A 3bjwA-2zbcA:
undetectable		 3bjwA-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC
(Sulfurisphaera
tokodaii) 		4 / 5 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.19A 3bjwG-2zbcA:
undetectable		 3bjwG-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC
(Sulfurisphaera
tokodaii) 		4 / 5 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.14A 3bjwC-2zbcA:
undetectable		 3bjwC-2zbcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2zbc 83AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR ASNC
(Sulfurisphaera
tokodaii) 		4 / 5 VAL A  42
VAL A  31
THR A  69
THR A  29
 None
None
ILE  A  84 (-3.6A)
None
 1.16A 3bjwD-2zbcA:
undetectable		 3bjwD-2zbcA:
22.32