SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 5 HIS A 189
SER A 122
LEU A 118
GLY A 398
 None
 1.07A 1a4lB-2zblA:
undetectable		 1a4lB-2zblA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 8 LEU A 257
LEU A 275
ALA A 278
LYS A 279
 None
 0.80A 1e7cA-2zblA:
undetectable		 1e7cA-2zblA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 PHE A 220
TRP A 224
GLU A 151
 None
 1.16A 1mogA-2zblA:
undetectable		 1mogA-2zblA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 VAL A 314
VAL A 299
TRP A 316
 None
None
BMA  A 501 (-3.8A)
 0.85A 1w5uA-2zblA:
undetectable
1w5uB-2zblA:
undetectable		 1w5uA-2zblA:
4.55
1w5uB-2zblA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 11 TYR A 329
THR A 324
LEU A 395
HIS A 258
TYR A 326
 None
 1.39A 2idkA-2zblA:
undetectable
2idkB-2zblA:
undetectable
2idkC-2zblA:
undetectable
2idkD-2zblA:
undetectable		 2idkA-2zblA:
20.95
2idkB-2zblA:
20.95
2idkC-2zblA:
20.95
2idkD-2zblA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 ASN A 231
ARG A 240
ASP A 167
 None
 0.93A 2qe6A-2zblA:
undetectable		 2qe6A-2zblA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 ASN A 231
ARG A 240
ASP A 167
 None
 0.96A 2qe6B-2zblA:
undetectable		 2qe6B-2zblA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 THR A 324
ALA A 327
LEU A 331
LEU A 395
LEU A 393
 None
 0.95A 2qxsB-2zblA:
undetectable		 2qxsB-2zblA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1162_1
(ALLERGEN ARG R 1)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 4 GLU A 179
ASP A 380
HIS A 383
GLU A 251
 None
BMA  A 501 ( 4.5A)
BMA  A 501 (-3.9A)
BMA  A 501 (-2.8A)
 1.27A 2x45A-2zblA:
0.0		 2x45A-2zblA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 7 TRP A  51
TYR A 382
GLN A 362
ILE A  52
 None
 1.13A 2xz5A-2zblA:
undetectable
2xz5B-2zblA:
undetectable		 2xz5A-2zblA:
18.00
2xz5B-2zblA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 7 GLN A 362
ILE A  52
TRP A  51
TYR A 382
 None
 1.16A 2xz5D-2zblA:
undetectable
2xz5E-2zblA:
undetectable		 2xz5D-2zblA:
18.00
2xz5E-2zblA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 ILE A 381
PHE A  21
HIS A 386
 None
 0.73A 3h0aA-2zblA:
undetectable		 3h0aA-2zblA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 GLY A 406
ALA A 405
SER A  61
PHE A  21
GLU A  14
 None
 1.47A 3s8pB-2zblA:
undetectable		 3s8pB-2zblA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDR_A_210A822_1
(ALPHA-BISABOLENE
SYNTHASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 4 ASP A 367
ASP A 365
ARG A 311
ASP A 293
 None
 1.43A 3sdrA-2zblA:
5.6		 3sdrA-2zblA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDV_A_911A822_0
(ALPHA-BISABOLENE
SYNTHASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 4 ASP A 367
ASP A 365
ARG A 311
ASP A 293
 None
 1.45A 3sdvA-2zblA:
5.6		 3sdvA-2zblA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 HIS A 386
ILE A 390
LEU A 328
ILE A 250
TYR A 382
 None
 1.26A 3sp9A-2zblA:
undetectable		 3sp9A-2zblA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 8 LEU A 198
VAL A 178
TYR A 185
LEU A 263
 None
 1.07A 3v81A-2zblA:
undetectable		 3v81A-2zblA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 8 LEU A 198
VAL A 178
TYR A 185
LEU A 263
 None
 1.07A 3v81C-2zblA:
undetectable		 3v81C-2zblA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 5 HIS A   9
LEU A 352
LEU A 384
ASP A 354
 None
 1.22A 4aqlA-2zblA:
undetectable		 4aqlA-2zblA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 GLY A 406
ALA A 405
SER A  61
PHE A  21
GLU A  14
 None
 1.46A 4bupA-2zblA:
undetectable		 4bupA-2zblA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 GLY A 406
ALA A 405
SER A  61
PHE A  21
GLU A  14
 None
 1.44A 4bupB-2zblA:
undetectable		 4bupB-2zblA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 6 GLU A 130
ILE A  79
ASN A  83
VAL A 184
 None
 1.11A 4ejwB-2zblA:
undetectable		 4ejwB-2zblA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 PHE A   4
LEU A 257
ALA A 321
ALA A 327
THR A 324
 None
 1.10A 4enhA-2zblA:
undetectable		 4enhA-2zblA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		3 / 3 LEU A 388
ILE A  20
ARG A  19
 None
 0.68A 4mk4B-2zblA:
undetectable		 4mk4B-2zblA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 ALA A 120
GLY A 119
ILE A  79
ASN A  83
ARG A 132
 None
 1.20A 4obwD-2zblA:
undetectable		 4obwD-2zblA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 6 TYR A 111
GLU A 251
TYR A 382
LEU A 118
 BMA  A 501 (-4.4A)
BMA  A 501 (-2.8A)
None
None
 1.24A 4twdB-2zblA:
2.1
4twdC-2zblA:
2.0		 4twdB-2zblA:
21.24
4twdC-2zblA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 GLY A 398
LEU A 399
ALA A 121
SER A 122
VAL A  62
 None
 0.96A 4wnwB-2zblA:
undetectable		 4wnwB-2zblA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 THR A 324
ALA A 327
LEU A 331
LEU A 395
LEU A 255
 None
 1.04A 4xi3C-2zblA:
undetectable		 4xi3C-2zblA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 11 ALA A 248
VAL A 208
ASP A 207
GLY A 170
PHE A 220
 None
 1.11A 4xp4A-2zblA:
undetectable		 4xp4A-2zblA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 9 ARG A  55
LEU A 118
GLY A 119
LEU A 385
GLU A 179
 BMA  A 501 (-2.7A)
None
None
None
None
 1.13A 5dqfA-2zblA:
undetectable		 5dqfA-2zblA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		4 / 8 ALA A 400
PRO A 397
LEU A 393
LEU A 407
 None
 1.06A 5dzkF-2zblA:
undetectable
5dzkT-2zblA:
undetectable		 5dzkF-2zblA:
19.90
5dzkT-2zblA:
1.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 2zbl PUTATIVE ISOMERASE
(Salmonella
enterica) 		5 / 12 GLY A 406
ALA A 405
SER A  61
PHE A  21
GLU A  14
 None
 1.41A 5wbvB-2zblA:
undetectable		 5wbvB-2zblA:
18.69