SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 LEU A  90
ILE A 187
LEU A 145
LEU A  76
LEU A 315
 None
 1.00A 1errB-2zbmA:
undetectable		 1errB-2zbmA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifA-2zbmA:
undetectable		 1kifA-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifB-2zbmA:
undetectable		 1kifB-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.25A 1kifC-2zbmA:
undetectable		 1kifC-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifD-2zbmA:
undetectable		 1kifD-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifE-2zbmA:
undetectable		 1kifE-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.25A 1kifF-2zbmA:
undetectable		 1kifF-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifG-2zbmA:
undetectable		 1kifG-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.24A 1kifH-2zbmA:
undetectable		 1kifH-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 ASP A 114
HIS A 150
HIS A  80
 ZN  A 402 ( 2.8A)
None
ZN  A 401 (-3.2A)
 0.63A 1oe1A-2zbmA:
undetectable		 1oe1A-2zbmA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 ASP A 114
HIS A 150
HIS A  80
 ZN  A 402 ( 2.8A)
None
ZN  A 401 (-3.2A)
 0.62A 1oe3A-2zbmA:
undetectable		 1oe3A-2zbmA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.25A 1ve9A-2zbmA:
undetectable		 1ve9A-2zbmA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 GLY A 208
GLY A 209
VAL A 300
SER A 262
LEU A 295
 None
 1.00A 1ya4B-2zbmA:
undetectable		 1ya4B-2zbmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 GLY A 208
GLY A 209
VAL A 300
SER A 262
LEU A 295
 None
 1.03A 1ya4C-2zbmA:
undetectable		 1ya4C-2zbmA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 ASN A 252
GLY A 208
TYR A 257
SER A  77
HIS A 207
 None
None
None
None
ZN  A 402 (-3.2A)
 1.48A 2cl5A-2zbmA:
1.3		 2cl5A-2zbmA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.28A 2du8G-2zbmA:
undetectable		 2du8G-2zbmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 5 TYR A 257
TYR A 260
ILE A 273
GLY A 253
 None
 1.18A 2du8J-2zbmA:
undetectable		 2du8J-2zbmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 7 GLY A  10
ASP A   9
ASN A 123
ASP A 167
 None
 1.03A 2g72B-2zbmA:
undetectable		 2g72B-2zbmA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 8 ASP A   9
TRP A  25
TYR A 181
TYR A  12
 None
 1.41A 2ha2A-2zbmA:
undetectable		 2ha2A-2zbmA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 8 ASP A   9
TRP A  25
TYR A 181
TYR A  12
 None
 1.42A 2ha2B-2zbmA:
undetectable		 2ha2B-2zbmA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 ASP A 114
HIS A 150
HIS A  80
 ZN  A 402 ( 2.8A)
None
ZN  A 401 (-3.2A)
 0.65A 2xxgA-2zbmA:
undetectable		 2xxgA-2zbmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 ASP A 114
HIS A 150
HIS A  80
 ZN  A 402 ( 2.8A)
None
ZN  A 401 (-3.2A)
 0.66A 2xxgC-2zbmA:
undetectable		 2xxgC-2zbmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 MET A 129
GLU A 151
ASN A 149
 None
None
ZN  A 402 (-2.7A)
 1.04A 3a27A-2zbmA:
undetectable		 3a27A-2zbmA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 THR A  53
ILE A 187
ASN A 101
ILE A  59
LEU A 145
 None
 1.23A 3a50E-2zbmA:
undetectable		 3a50E-2zbmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 THR A  53
ILE A 187
ASN A 101
ILE A  59
LEU A 145
 None
 1.24A 3a51D-2zbmA:
undetectable		 3a51D-2zbmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 THR A  53
ILE A 187
ASN A 101
ILE A  59
LEU A 145
 None
 1.21A 3a51E-2zbmA:
undetectable		 3a51E-2zbmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 7 VAL A 154
ASP A 114
HIS A  80
TYR A 177
 None
ZN  A 402 ( 2.8A)
ZN  A 401 (-3.2A)
None
 1.00A 3avpA-2zbmA:
undetectable		 3avpA-2zbmA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 HIS A 144
HIS A 108
MET A 142
 None
 0.48A 3mihA-2zbmA:
undetectable		 3mihA-2zbmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		5 / 12 HIS A  80
ILE A 307
LEU A  86
LEU A 132
MET A 129
 ZN  A 401 (-3.2A)
None
None
None
None
 1.32A 3vn2A-2zbmA:
undetectable		 3vn2A-2zbmA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 7 VAL A 284
VAL A 300
LEU A 295
ASN A 252
 None
 1.04A 4e1gB-2zbmA:
undetectable		 4e1gB-2zbmA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		3 / 3 ASP A 243
LEU A 244
PHE A 247
 None
 0.65A 4pthA-2zbmA:
undetectable		 4pthA-2zbmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 7 ALA A  75
ASP A 133
ARG A 137
GLY A 141
 None
 1.02A 5bs8A-2zbmA:
undetectable
5bs8B-2zbmA:
undetectable
5bs8C-2zbmA:
undetectable		 5bs8A-2zbmA:
21.15
5bs8B-2zbmA:
21.79
5bs8C-2zbmA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 8 THR A 170
LEU A 172
ILE A  26
LEU A  31
 None
 0.88A 5g48A-2zbmA:
undetectable		 5g48A-2zbmA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 4 ASP A 114
HIS A 207
HIS A 286
HIS A 150
 ZN  A 402 ( 2.8A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.2A)
None
 1.49A 5ncdD-2zbmA:
undetectable		 5ncdD-2zbmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2zbm PROTEIN-TYROSINE-PHO
SPHATASE
(Shewanella
sp.) 		4 / 6 MET A 115
GLY A 285
ALA A  75
LEU A  76
 None
 1.04A 6fosA-2zbmA:
undetectable		 6fosA-2zbmA:
12.97