SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		4 / 5 THR A1046
LEU A1044
VAL A1027
LEU A1034
 None
 0.87A 1fbmE-2zd2A:
undetectable		 1fbmE-2zd2A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		5 / 12 GLY A1097
VAL A1150
LEU A1151
LEU A1154
LEU A1102
 None
 0.91A 1mx1F-2zd2A:
undetectable		 1mx1F-2zd2A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		5 / 12 ILE A1190
VAL A1185
GLY A1182
LEU A1101
PRO A1176
 None
 1.07A 3em0B-2zd2A:
undetectable		 3em0B-2zd2A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		4 / 4 LEU A1044
PRO A1045
LEU A1049
ILE A1053
 None
 0.97A 4f4dB-2zd2A:
undetectable		 4f4dB-2zd2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		5 / 9 ALA A1195
THR A1194
ILE A1186
GLY A1188
ALA A1184
 None
 1.01A 4qvqK-2zd2A:
undetectable
4qvqL-2zd2A:
undetectable		 4qvqK-2zd2A:
22.92
4qvqL-2zd2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		5 / 9 ALA A1195
THR A1194
ILE A1186
GLY A1188
ALA A1184
 None
 1.01A 4qvqY-2zd2A:
undetectable
4qvqZ-2zd2A:
undetectable		 4qvqY-2zd2A:
22.92
4qvqZ-2zd2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		5 / 10 VAL A1185
LEU A1071
ALA A1192
PRO A1176
LEU A1175
 None
 1.29A 5mm4B-2zd2A:
undetectable		 5mm4B-2zd2A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 2zd2 ATP12 ATPASE
(Paracoccus
denitrificans) 		4 / 5 PRO A1163
VAL A1082
GLY A1182
VAL A1158
 None
 1.02A 6ak3B-2zd2A:
undetectable		 6ak3B-2zd2A:
17.82